PRODUCT DETAILS
| Sodium dehydroacetate Basic information |
| Product Name: |
Sodium dehydroacetate |
| Synonyms: |
Sodium 1-(3,4-dihydro-6-methyl-2,4-dioxo-2H-pyran-3-ylidene)ethanolate;SODIUM 3-ACETYL-4-HYDROXY-6-METHYL-2-OXO-4(2H)-PYRANOLATE;SODIUM DEHYDROACETATE;2H-Pyran-2,4(3H)-dione,3-acetyl-6-methyl-,ion(1-),sodium;3-(1-hydroxyethylidene)-6-methyl-2h-pyran-2,4(3h)-dione,sodiumsalt[qr];4(3h)-dione,3-acetyl-6-methyl-2h-pyran-sodiumsalt;4(3h)-dione,3-acetyl-6-methyl-2h-pyran-sodiumsalt[qr];4-hexenoicacid,2-acetyl-5-hydroxy-3-oxo,delta-lactone,sodiumderiv. |
| CAS: |
4418-26-2 |
| MF: |
C8H7NaO4 |
| MW: |
190.13 |
| EINECS: |
224-580-1 |
| Product Categories: |
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| Mol File: |
4418-26-2.mol |
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| Sodium dehydroacetate Chemical Properties |
| Melting point |
~295 °C (dec.) |
| storage temp. |
Store below +30°C. |
| solubility |
330g/l |
| form |
Powder |
| color |
White to yellow |
| PH |
8.8-9.3 (100g/l, H2O, 20℃) |
| Water Solubility |
Soluble in water, propylene glycol and methanol. Insoluble in acetone and benzene. |
| BRN |
4893653 |
| Stability: |
Stable. Incompatible with strong oxidizing agents. |
| InChIKey |
ZPNRBQVNNIDJHX-UHFFFAOYSA-M |
| CAS DataBase Reference |
4418-26-2(CAS DataBase Reference) |
| EPA Substance Registry System |
3-Acetyl-6-methyl-2H-pyran-2,4(3H)-dione sodium (4418-26-2) |
| Hazard Codes |
Xn |
| Risk Statements |
22 |
| Safety Statements |
24/25 |
| WGK Germany |
1 |
| RTECS |
UP8225000 |
| Autoignition Temperature |
360 °C |
| TSCA |
Yes |
| HS Code |
29322980 |
| Hazardous Substances Data |
4418-26-2(Hazardous Substances Data) |
| Toxicity |
LD50 orally in Rabbit: 500 mg/kg |
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| Sodium dehydroacetate Usage And Synthesis |
| Description |
Sodium dehydroacetate is the sodium salt of dehydroacetate. It is mainly used as a new generation food preservative and food additive, being used extensively in sauce, fruit, bread, cake, moon cake, margarine and beverage. Sodium dehydroacetate (DHA-S) has a wide spectrum of antimicrobial activity that accounts for its use in cosmetic products as a preservative and antimicrobial agent. It is effective in the treatment of both bacteria and fungi. It is also a kind of anticoagulant agent through depleting the blood level of vitamin K. |
| Chemical Properties |
White to yellowish powder |
| Uses |
Dehydroacetic acid sodium salt (DHS-Na) is used in the food industry as preservative for fruits, vegetables, fruit juice, honey, beer, milk, protein and fat products; in human and veterinary medicine as bactericide and fungicide. Product Data Sheet |
| Uses |
Geogard(R) 111S preservative is based on dehydroacetic acid (DHA), the sodium salt form (NaDHA) and therefore are recognized by major cosmetic, toiletry and fragrance regulatory authorities worldwide for use in cosmetic and personal care products. |
| Uses |
sodium dehydroacetate is a preservative against bacteria and fungi that is used at concentration levels of 1.0 percent or less. It is useful in combination with parabens. It may cause skin irritation. |
| General Description |
White powder. Used as a fungicide, plasticizer, toothpaste, preservative in food. |
| Air & Water Reactions |
Water soluble. |
| Reactivity Profile |
Sodium dehydroacetate reacts with acids. May react viogrously with strong oxidizing acids. |
| Safety Profile |
Poison by intravenous route. Moderately toxic by ingestion. An experimental teratogen. Experimental reproductive effects. An eye irritant. Mutation data reported. When heated to decomposition it emits toxic fumes of Na2O |
| References |
Forester, John. "Preservative solutions containing sodium dehydroacetate with or without sodium borate decahydrate and/or disodium edetate." US, US4248634. 1981.
Sakaguchi, Yuka, et al. "Anticoagulant effect of sodium dehydroacetate (DHA-S) in rats." Journal of Applied Toxicology 28.4(2008):524-529.
Ye, Yinzhi. "Use of Sodium Dehydroacetate in Food." China Food Additives (2002). |
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| Sodium dehydroacetate Preparation Products And Raw materials |
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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
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