Product Certification&
    Enterprise Certification

  • Mr.Leader Biogroup
    Tel: 86-029-68895030

  • Ms.Kelly
    Sales manager
    Tel: 029-68569962

  • Mobile:86-029-68895030
  • Tel:86-029-68895030
  • Fax:86-029-68569961
  • URL:http://www.leaderbio-ingredients.com
  • Province/state:Shaanxi
  • City:Xi'an
  • Street:Aerospace Economic & Technical Development Zone, Chang'an District,Xi'an,China
  • MaxCard:
Home > Products >  China Largest Manufacturer factory sales Indazole-3-carboxylic acid CAS 4498-67-3

China Largest Manufacturer factory sales Indazole-3-carboxylic acid CAS 4498-67-3 CAS NO.4498-67-3

  • FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
  • Min.Order: 500 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Available Specifications:

    AAAAA(50-100)KilogramAAAAA(100-500)Kilogram

  • Product Details

Keywords

  • Indazole-3-carboxylic acid
  • Indazole-3-carboxylic acid
  • 4498-67-3

Quick Details

  • ProName: China Largest Manufacturer factory sal...
  • CasNo: 4498-67-3
  • Molecular Formula: 4498-67-3
  • Appearance: white powder
  • Application: Pharm chemicals industry
  • DeliveryTime: 3-5 days
  • PackAge: 25KG/Drum
  • Port: Shanghai Guangzhou Qingdao Shenzhen
  • ProductionCapacity: 20 Metric Ton/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By air /Sea/ coruier
  • LimitNum: 500 Kilogram
  • Heavy metal: 10PPM
  • Color: red
  • Melting point: ≥350°C
  • Boiling point: 363.24°C (rough estimate)
  • density: 1.667
  • solubility: 1 M NaOH: 10 mg/mL, dark green
  • Water Solubility: <0.1 g/100 mL at 21 oC
  • Stability: Stable. Combustible. Incompatible with...

Superiority

                                PRODUCT DETAILS       

7-Hydroxygranisetron Basic information
Product Name: 7-Hydroxygranisetron
Synonyms: 1H-INDAZOL-3-CARBONIC ACID;1H-INDAZOLE-3-CARBOXYLIC ACID;1H-INDAZOLE-3-CARBONIC ACID;AKOS BB-9978;3-INDAZOLECARBOXYLIC ACID;3-CARBOXYINDAZOLE;ndazole-3-carboxylic acid;INDAZOLE-3-CARBOXYLIC ACID
CAS: 4498-67-3
MF: C8H6N2O2
MW: 162.15
EINECS: 224-794-5
Product Categories: Indoles and derivatives;pharmacetical;Acids and Derivatives;Heterocycles;Carboxylic Acids;Organic acids;PHARMACEUTICAL INTERMEDIATES;(intermediate of granisetron);Indazoles;Indole Derivatives;Carboxylic Acids;Fused Ring Systems;Building Blocks;Heterocyclic Building Blocks
Mol File: 4498-67-3.mol
7-Hydroxygranisetron Structure
 
7-Hydroxygranisetron Chemical Properties
Melting point  266-270 °C (dec.)
Boiling point  443.7±18.0 °C(Predicted)
density  1.506±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
pka 3.03±0.10(Predicted)
form  powder
color  beige
BRN  6354
InChIKey BHXVYTQDWMQVBI-UHFFFAOYSA-N
CAS DataBase Reference 4498-67-3(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36-36/37/38
Safety Statements  26-36/37/39-22
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT
HS Code  29339900
MSDS Information
Provider Language
SigmaAldrich English
 
7-Hydroxygranisetron Usage And Synthesis
Chemical Properties yellow crystal
Uses Indazole-3-carboxylic acid is indole derivatives useful in treatment of pain and inflammation
Uses Indazole-3-carboxylic acid may be used in the synthesis of the following:
  • N-(8-methyl-azabicyclo[3.2.11]oct-3-yl)-1H-indazole-3-carboxamide
  • N-(1- benzyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-1H-indazole-3-carboxamide
  • 1H-indazole-3-carboxamide
Synthesis Reference(s) Journal of Heterocyclic Chemistry, 26, p. 531, 1989 DOI: 10.1002/jhet.5570260251
 
7-Hydroxygranisetron Preparation Products And Raw materials
Raw materials Sodium hydroxide-->Hydrochloric acid-->Sulfuric acid-->Acetic acid-->Sodium nitrite-->Stannous chloride dihydrate-->STANNOUS CHLORIDE-->Isatin
Preparation Products Lonidamine-->3-Methylindole-->1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE-->5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE-->1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
 

                                                              About US 
Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

                                                                       Group profiles

Our Factories production lines

                                                   Our Factories R&D ability

                        Our Factories warehouse 

                

Details

                                                       Product information

7-Hydroxygranisetron Basic information
Product Name: 7-Hydroxygranisetron
Synonyms: 1H-INDAZOL-3-CARBONIC ACID;1H-INDAZOLE-3-CARBOXYLIC ACID;1H-INDAZOLE-3-CARBONIC ACID;AKOS BB-9978;3-INDAZOLECARBOXYLIC ACID;3-CARBOXYINDAZOLE;ndazole-3-carboxylic acid;INDAZOLE-3-CARBOXYLIC ACID
CAS: 4498-67-3
MF: C8H6N2O2
MW: 162.15
EINECS: 224-794-5
Product Categories: Indoles and derivatives;pharmacetical;Acids and Derivatives;Heterocycles;Carboxylic Acids;Organic acids;PHARMACEUTICAL INTERMEDIATES;(intermediate of granisetron);Indazoles;Indole Derivatives;Carboxylic Acids;Fused Ring Systems;Building Blocks;Heterocyclic Building Blocks
Mol File: 4498-67-3.mol
7-Hydroxygranisetron Structure
 
7-Hydroxygranisetron Chemical Properties
Melting point  266-270 °C (dec.)
Boiling point  443.7±18.0 °C(Predicted)
density  1.506±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Methanol (Slightly)
pka 3.03±0.10(Predicted)
form  powder
color  beige
BRN  6354
InChIKey BHXVYTQDWMQVBI-UHFFFAOYSA-N
CAS DataBase Reference 4498-67-3(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xn,Xi
Risk Statements  22-36-36/37/38
Safety Statements  26-36/37/39-22
WGK Germany  3
Hazard Note  Irritant
HazardClass  IRRITANT
HS Code  29339900
MSDS Information
Provider Language
SigmaAldrich English
 
7-Hydroxygranisetron Usage And Synthesis
Chemical Properties yellow crystal
Uses Indazole-3-carboxylic acid is indole derivatives useful in treatment of pain and inflammation
Uses Indazole-3-carboxylic acid may be used in the synthesis of the following:
  • N-(8-methyl-azabicyclo[3.2.11]oct-3-yl)-1H-indazole-3-carboxamide
  • N-(1- benzyl-4-methylhexahydro-1H-1,4-diazepin-6-yl)-1H-indazole-3-carboxamide
  • 1H-indazole-3-carboxamide
Synthesis Reference(s) Journal of Heterocyclic Chemistry, 26, p. 531, 1989 DOI: 10.1002/jhet.5570260251
 
7-Hydroxygranisetron Preparation Products And Raw materials
Raw materials Sodium hydroxide-->Hydrochloric acid-->Sulfuric acid-->Acetic acid-->Sodium nitrite-->Stannous chloride dihydrate-->STANNOUS CHLORIDE-->Isatin
Preparation Products Lonidamine-->3-Methylindole-->1H-INDAZOLE-3-(N-METHOXY-METHYL)CARBAMIDE-->5-BROMO-1H-INDAZOLE-3-CARBALDEHYDE-->1H-INDAZOLE-3-CARBOXYLIC ACID ETHYL ESTER
 

 

Other products of this supplier

lookchemhot product CAS New CAS Cas Database Article Data Chemical Catalog