China Largest Manufacturer factory Supply GHK-Cu/Glycyl-L-Histidyl-L-Lysine CAS 49557-75-7 CAS NO.49557-75-7

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Copper Peptide Basic information Product Name: Copper Peptide Synonyms: GHK Cu Copper Peptide;L-Lysine,glycyl-L-histidyl-;Copper Peptide powder (GHK-cu);GHK Cu Copper Peptide GHK.Cu GHK-Cu;Ahk-cu;Liver Cell Growth Factor(GHK);GHKcu/Growth-Modulating peptide;(Gly-His-Lys)2Cu.xHAc CAS: 49557-75-7 MF: C14H24N6O4 MW: 340.38 EINECS: 1592732-453-0 Product Categories: BEAUTY PEPTIDES;cosmestic;APIs Mol File: 49557-75-7.mol   Copper Peptide Chemical Properties Melting point  >144°C (dec.) Boiling point  831.0±65.0 °C(Predicted) density  1.324 storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C solubility  Aqueous Acid (Slightly), DMSO (Slightly) form  Solid pka 3.11±0.10(Predicted) color  Off-White Stability: Hygroscopic   Safety Information MSDS Information   Copper Peptide Usage And Synthesis Description Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine. Uses Copper Peptide(GHK-Cu) can be used as skin antiaging agents. Uses anti-wrikle Uses Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production. Definition ChEBI: A tripeptide composed of glycine, L-histidine and L-lysine residues joined in sequence. Pharmaceutical Applications Glycyl-l-histidyl-l-lysine (GHK) is a tripeptide known for its high binding affinity to Cu2+ and its complex role in wound healing. The GHK–Cu(II) complex was isolated from human plasma in the 1970s and it was shown to be an activator for wound healing. GHK–Cu(II) has two main functions: as an anti-inflammatory agent to protect the tissue from oxidative damage after the injury, and as an activator for wound healing itself as it activates the tissue remodelling. The structure of GHK is very similar to that of common drugs used to treat ulcers. After the initial stages of wound healing are activated, such as blood coagulation and neutrophil invasion, a second stage of wound healing begins, which includes the population of GHK at the wound, which has a high affinity to Cu2+. Mast cells, which are located in the skin, secrete GHK, which accumulates Cu2+ and forms the copper complex GHK–Cu(II) and therefore increases the metal–tripeptide concentration at the wound. First, GHK–Cu(II) has an anti-inflammatory effect by protecting the tissue from oxidative damage and by suppressing local inflammatory signals (i.e. cytokine interleukin-1 (IL-1)). Second, GHK–Cu(II) is released into the blood stream and encourages the production of wound macrophages that support the wound repair by removing the damaged tissue and secreting a family of several growth factor proteins. GHK–Cu(II) also hinders fibroblast production of TGF-β-1 and therefore suppresses the scar development. The GHK–Cu(II) complex also stimulates the growth of blood vessels, neurons and elastin, and, in general, supports most processes of wound healing.   Copper Peptide Preparation Products And Raw materials

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Copper Peptide Basic information Product Name: Copper Peptide Synonyms: GHK Cu Copper Peptide;L-Lysine,glycyl-L-histidyl-;Copper Peptide powder (GHK-cu);GHK Cu Copper Peptide GHK.Cu GHK-Cu;Ahk-cu;Liver Cell Growth Factor(GHK);GHKcu/Growth-Modulating peptide;(Gly-His-Lys)2Cu.xHAc CAS: 49557-75-7 MF: C14H24N6O4 MW: 340.38 EINECS: 1592732-453-0 Product Categories: BEAUTY PEPTIDES;cosmestic;APIs Mol File: 49557-75-7.mol   Copper Peptide Chemical Properties Melting point  >144°C (dec.) Boiling point  831.0±65.0 °C(Predicted) density  1.324 storage temp.  under inert gas (nitrogen or Argon) at 2–8 °C solubility  Aqueous Acid (Slightly), DMSO (Slightly) form  Solid pka 3.11±0.10(Predicted) color  Off-White Stability: Hygroscopic   Safety Information MSDS Information   Copper Peptide Usage And Synthesis Description Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine. Uses Copper Peptide(GHK-Cu) can be used as skin antiaging agents. Uses anti-wrikle Uses Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production. Definition ChEBI: A tripeptide composed of glycine, L-histidine and L-lysine residues joined in sequence. Pharmaceutical Applications Glycyl-l-histidyl-l-lysine (GHK) is a tripeptide known for its high binding affinity to Cu2+ and its complex role in wound healing. The GHK–Cu(II) complex was isolated from human plasma in the 1970s and it was shown to be an activator for wound healing. GHK–Cu(II) has two main functions: as an anti-inflammatory agent to protect the tissue from oxidative damage after the injury, and as an activator for wound healing itself as it activates the tissue remodelling. The structure of GHK is very similar to that of common drugs used to treat ulcers. After the initial stages of wound healing are activated, such as blood coagulation and neutrophil invasion, a second stage of wound healing begins, which includes the population of GHK at the wound, which has a high affinity to Cu2+. Mast cells, which are located in the skin, secrete GHK, which accumulates Cu2+ and forms the copper complex GHK–Cu(II) and therefore increases the metal–tripeptide concentration at the wound. First, GHK–Cu(II) has an anti-inflammatory effect by protecting the tissue from oxidative damage and by suppressing local inflammatory signals (i.e. cytokine interleukin-1 (IL-1)). Second, GHK–Cu(II) is released into the blood stream and encourages the production of wound macrophages that support the wound repair by removing the damaged tissue and secreting a family of several growth factor proteins. GHK–Cu(II) also hinders fibroblast production of TGF-β-1 and therefore suppresses the scar development. The GHK–Cu(II) complex also stimulates the growth of blood vessels, neurons and elastin, and, in general, supports most processes of wound healing.   Copper Peptide Preparation Products And Raw materials