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Home > Products >  China Biggest Factory & Manufacturer supply Acetyl-L-carnitine hydrochloride 500MT/Year

China Biggest Factory & Manufacturer supply Acetyl-L-carnitine hydrochloride 500MT/Year CAS NO.5080-50-2

  • FOB Price: USD: 1.00-2.00 /Kilogram Get Latest Price
  • Min.Order: 500 Kilogram
  • Payment Terms: L/C,D/A,D/P,T/T,MoneyGram,Other
  • Available Specifications:

    AAAAA(50-100)KilogramAAAAA(100-500)Kilogram

  • Product Details

Keywords

  • Acetyl-L-carnitine hydrochloride
  • Acetyl-L-carnitine hydrochloride
  • 5080-50-2

Quick Details

  • ProName: China Biggest Factory & Manufacturer s...
  • CasNo: 5080-50-2
  • Molecular Formula: 5080-50-2
  • Appearance: white powder
  • Application: chemicals industry
  • DeliveryTime: 3-5 days
  • PackAge: 25KG/Drum
  • Port: Shanghai Guangzhou Qingdao Shenzhen
  • ProductionCapacity: 20 Metric Ton/Month
  • Purity: 99%
  • Storage: 2-8°C
  • Transportation: By air /Sea/ coruier
  • LimitNum: 500 Kilogram
  • Color: white
  • Melting point: ≥350°C
  • Boiling point: 363.24°C (rough estimate)
  • density: 1.667
  • solubility: 1 M NaOH: 10 mg/mL, dark green
  • Water Solubility: <0.1 g/100 mL at 21 oC
  • Stability: Stable. Combustible. Incompatible with...

Superiority

O-Acetyl-L-carnitine hydrochloride Basic information
Product Name: O-Acetyl-L-carnitine hydrochloride
Synonyms: ACETYL-L-CARNITINE HCL(SH);(R)-2-acetoxy-3-carboxy-N,N,N-triMethylpropan-1-aMiniuM chloride;O-Acetylcarnitine (hydrochloride);R(-)-2-ACETYLOXY-3-CARBOXYN,N,N-TRIMETHYL1-PROPANAMINIUM CHLORIDE;R-(-)-2-ACETYLOXY-3-CARBOXY-N,N,N-TRIMETHYL-1-PROPANAMINIUM HYDROCHLORIDE;R-(-)-2-ACETOXY-3-CARBOXY-N,N,N-TRIMETHYL-1-PROPANAMINIUM HYDROCHLORIDE;(R)-3-ACETOXY-4-(TRIMETHYLAMMONIO)BUTYRATE HYDROCHLORIDE;O-ACETYL-L-CARNITINE CHLORIDE
CAS: 5080-50-2
MF: C9H18ClNO4
MW: 239.7
EINECS: 1308068-626-2
Product Categories: L-Carnitine Series;Chiral Compound;Lipid signaling;co-factor;Inhibitors;Pyridines
Mol File: 5080-50-2.mol
O-Acetyl-L-carnitine hydrochloride Structure
 
O-Acetyl-L-carnitine hydrochloride Chemical Properties
Melting point  194 °C (dec.)(lit.)
alpha  -29 º (c=1, H2O)
refractive index  -28 ° (C=1, H2O)
storage temp.  2-8°C
solubility  H2O: 100 mg/mL
form  powder
color  white
optical activity [α]25/D 28°, c = 2 in H2O(lit.)
Water Solubility  soluble
Sensitive  Hygroscopic
Merck  14,84
BRN  4340103
InChIKey JATPLOXBFFRHDN-DDWIOCJRSA-N
CAS DataBase Reference 5080-50-2(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
F  3-9
HS Code  29239000
MSDS Information
Provider Language
ACROS English
SigmaAldrich English
 
O-Acetyl-L-carnitine hydrochloride Usage And Synthesis
Description Levacecarnine hydrochloride is a nootropic agent structurally related to the natural substance L-carnitine. It is reported to be useful in the treatment of cognition disorders in the elderly, perhaps due to its weak cholinergic properties.
Description Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine (Item No. 21489) that is catabolized by plasma esterases into carnitine. Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund''s adjuvant.
Chemical Properties Crystallline powder
Originator Sigma-Tau (Italy)
Uses O-Acetyl-L-carnitine hydrochloride is used as a cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.
Uses Acetyl-L-Carnitine (ALC) is an important dietary supplement. ALC is a natural substance, present in the human body, especially in muscles, in the brain, and in the male testicles. ALC is the acetylated, high-energy form of L-Carnitine.
Uses

O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.
Brand name NICETILE; BRANICEN
General Description

Acetyl-L-carnitine (ALC/ALCAR), a quasi-vitamin is a metabolite of carnitine, present in mammalian plasma and tissues. It is the acetylated form of L-carnitine (LC). ALCAR is used as a dietary supplement. It is present at high level in the hypothalamus.
Biochem/physiol Actions Acetyl L-carnitine (ALC) plays a vital role in intermediary metabolism and in improving female fertility. The oxidative and metabolic status of the female reproductive system is controlled by ALC. ALC possesses cholinomimetic and anti-inflammatory effects. It controls γ-amino butyric acid (GABA) system. ALC is capable of modifying the rate of glucose usage in the brain. It also possesses a neuroprotective role in the developing brain.
Purification Methods Recrystallise the chloride from isopropanol. Dry it over P2O5 under high vacuum. The S-betaine crystallises from EtOH/Et2O with m 145o(dec) and is hygroscopic; it has [] D -19.5o (c 6, H2O). [Krimberg & Wittandt Biochem Z 251 231 1932, Strack et al. Z Physiol Chem 238 191 1936, Beilstein 4 III 1630, 1632.]
 
O-Acetyl-L-carnitine hydrochloride Preparation Products And Raw materials
Preparation Products L-Acetylcarnitine
 

Details

O-Acetyl-L-carnitine hydrochloride Basic information
Product Name: O-Acetyl-L-carnitine hydrochloride
Synonyms: ACETYL-L-CARNITINE HCL(SH);(R)-2-acetoxy-3-carboxy-N,N,N-triMethylpropan-1-aMiniuM chloride;O-Acetylcarnitine (hydrochloride);R(-)-2-ACETYLOXY-3-CARBOXYN,N,N-TRIMETHYL1-PROPANAMINIUM CHLORIDE;R-(-)-2-ACETYLOXY-3-CARBOXY-N,N,N-TRIMETHYL-1-PROPANAMINIUM HYDROCHLORIDE;R-(-)-2-ACETOXY-3-CARBOXY-N,N,N-TRIMETHYL-1-PROPANAMINIUM HYDROCHLORIDE;(R)-3-ACETOXY-4-(TRIMETHYLAMMONIO)BUTYRATE HYDROCHLORIDE;O-ACETYL-L-CARNITINE CHLORIDE
CAS: 5080-50-2
MF: C9H18ClNO4
MW: 239.7
EINECS: 1308068-626-2
Product Categories: L-Carnitine Series;Chiral Compound;Lipid signaling;co-factor;Inhibitors;Pyridines
Mol File: 5080-50-2.mol
O-Acetyl-L-carnitine hydrochloride Structure
 
O-Acetyl-L-carnitine hydrochloride Chemical Properties
Melting point  194 °C (dec.)(lit.)
alpha  -29 º (c=1, H2O)
refractive index  -28 ° (C=1, H2O)
storage temp.  2-8°C
solubility  H2O: 100 mg/mL
form  powder
color  white
optical activity [α]25/D 28°, c = 2 in H2O(lit.)
Water Solubility  soluble
Sensitive  Hygroscopic
Merck  14,84
BRN  4340103
InChIKey JATPLOXBFFRHDN-DDWIOCJRSA-N
CAS DataBase Reference 5080-50-2(CAS DataBase Reference)
 
Safety Information
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
F  3-9
HS Code  29239000
MSDS Information
Provider Language
ACROS English
SigmaAldrich English
 
O-Acetyl-L-carnitine hydrochloride Usage And Synthesis
Description Levacecarnine hydrochloride is a nootropic agent structurally related to the natural substance L-carnitine. It is reported to be useful in the treatment of cognition disorders in the elderly, perhaps due to its weak cholinergic properties.
Description Acetyl-L-carnitine is an acetylated form of the essential mitochondrial metabolite L-carnitine (Item No. 21489) that is catabolized by plasma esterases into carnitine. Acetyl-L-carnitine facilitates the uptake of acetyl-CoA into mitochondria during fatty acid oxidation, enhances acetylcholine production, and stimulates protein and membrane phospholipid synthesis. In vivo, acetyl-L-carnitine (100 mg/kg) increases mGlu2/3 receptor protein levels and mechanical pain thresholds in a mouse model of chronic inflammatory pain induced by complete Freund''s adjuvant.
Chemical Properties Crystallline powder
Originator Sigma-Tau (Italy)
Uses O-Acetyl-L-carnitine hydrochloride is used as a cholinergic agonist that stimulates neuronal response to serotonin and acetylcholine. Acetylcarnitine has antinociceptive activity that may be mediated by enhanced activity of muscarinic cholinergic receptors or mGlu2 glutamate receptors.
Uses Acetyl-L-Carnitine (ALC) is an important dietary supplement. ALC is a natural substance, present in the human body, especially in muscles, in the brain, and in the male testicles. ALC is the acetylated, high-energy form of L-Carnitine.
Uses

O-Acetyl-L-carnitine hydrochloride may be used as a precursor for the preparation of O-Acetyl-L-carnitine, which in turn may be used as an analytical reference standard for the determination of the analyte in biological samples by hydrophilic interaction liquid chromatography-tandem mass spectrometry (HILIC-MS/MS) technique.
Brand name NICETILE; BRANICEN
General Description

Acetyl-L-carnitine (ALC/ALCAR), a quasi-vitamin is a metabolite of carnitine, present in mammalian plasma and tissues. It is the acetylated form of L-carnitine (LC). ALCAR is used as a dietary supplement. It is present at high level in the hypothalamus.
Biochem/physiol Actions Acetyl L-carnitine (ALC) plays a vital role in intermediary metabolism and in improving female fertility. The oxidative and metabolic status of the female reproductive system is controlled by ALC. ALC possesses cholinomimetic and anti-inflammatory effects. It controls γ-amino butyric acid (GABA) system. ALC is capable of modifying the rate of glucose usage in the brain. It also possesses a neuroprotective role in the developing brain.
Purification Methods Recrystallise the chloride from isopropanol. Dry it over P2O5 under high vacuum. The S-betaine crystallises from EtOH/Et2O with m 145o(dec) and is hygroscopic; it has [] D -19.5o (c 6, H2O). [Krimberg & Wittandt Biochem Z 251 231 1932, Strack et al. Z Physiol Chem 238 191 1936, Beilstein 4 III 1630, 1632.]
 
O-Acetyl-L-carnitine hydrochloride Preparation Products And Raw materials
Preparation Products L-Acetylcarnitine

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