PRODUCT DETAILS
1. Chemical Name: Copper Gluconate
2. Molecular Formula: C12H 22CuO14 Anhydrous
3. Structural Formula:
4. Molecular Weight: 453.84 Anhydrous
5. CAS No.: 527-09-3
6. Specification: USP/FCC/BP grade
7. Characters: Light blue green powder that is soluble in water and slightly soluble in alcohol.
8. Application: Nutrient.
a. Trace mineral that is essential to bone formation and the maintenance of healthy nerves;
b. Facilitates iron absorption, hemoglobin, and red blood cells;
c. Helps body to oxidize vitamin C;
d. Works with Zinc anc Vitamin C to form elastin;
e. Aids in the production of RNA;
f. Copper nutrition enhancer: Used in dairy products, baby and child foods;
9. Package: Fiber drum or all paper drum or kraft paper bag, 25Kg net each
10. Storage: Stored in well-closed containers in a dry place at room temperature
11. Transportation: Handle with care in order to avoid damaging the package, protect them from sunshine or rain.
| Item |
Specification |
| USP |
FCC |
|
| Assay |
98.0-102.0% |
98% max |
Copper content: 13.72%-14.28%(calculated from assay on as is basis) |
| Identification |
AB(+) |
AB |
| Chloride |
0.07% max |
|
| Sulfate |
0.05% max |
|
Solubility: soluble in water (10g in 100ml at 25°C) |
| Arsenic |
3ppm max |
3ppm max |
| Lead |
25ppm max |
10ppm max |
Bulk density: 0.90±0.02g/cm3 |
| Reducing Substances |
1.0% max |
0.1% max |
| |
| Copper(II) gluconate Chemical Properties |
| Melting point |
155-157 °C(lit.) |
| refractive index |
16.5 ° (C=1, H2O) |
| storage temp. |
Inert atmosphere,Room Temperature |
| solubility |
Aqueous Acid (Slightly), Water (Sparingly, Sonicated) |
| form |
powder |
| color |
Light Blue to Blue |
| optical activity |
[α]26/D +15°, c = 1 in H2O |
| Water Solubility |
slightly soluble |
| Merck |
14,2640 |
| Stability: |
Hygrscopic |
| CAS DataBase Reference |
527-09-3(CAS DataBase Reference) |
| EPA Substance Registry System |
Copper gluconate (527-09-3) |
| Provider |
Language |
| D-Gluconic acid copper(II) salt |
English |
| ACROS |
English |
| SigmaAldrich |
English |
| ALFA |
English |
| |
| Copper(II) gluconate Usage And Synthesis |
| Description |
Copper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram. |
| References |
Dicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92. |
| Chemical Properties |
Copper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol. |
| Uses |
Supplement (trace mineral). |
| Uses |
copper gluconate is cited as having skin-conditioning and skinprotecting functions. |
| Uses |
Copper(II) gluconate is used in dietary supplement. It is also used to treat acne vulgaris, common cold, hypertension, premature labor, leishmaniasis and visceral postoperative complications. Further, it is used in oral deodorants and feed additives. In addition to this, it is used as a synergist and nutritional supplement for foods. It is the active component in retsyn used in mints and certs. |
| Preparation |
Copper(II) gluconate is prepared by the dissolution of copper(II) carbonate or copper(II) hydroxide in gluconic acid. It is used as a nutritional supplement for copper deficiency and as a component in oral deodorants. |
| Safety Profile |
When heated to decomposition it emits acrid smoke and irritating fumes. |
| |
| Copper(II) gluconate Preparation Products And Raw materials |
About US
Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research. Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products. Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation. We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.
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