China Largest factory Manufacturer Supply PHYTOSPHINGOSINE CAS 554-62-1 CAS NO.554-62-1

                   About Product Technical Details 

PHYTOSPHINGOSINE Basic information Product Name: PHYTOSPHINGOSINE Synonyms: PHYTOSPHINGOSINE;PHYTOSPHINGOSINE HYDROCHLORIDE;(2S, 3S, 4R)-2-AMINO-1,3,4-OCTADECANETRIOL 4-HYDROXYSPHINGANINE;4-HYDROXYSPHINGANINE;1,3,4-Octadecanetriol,2-amino-, (2S, 3S, 4R) -;(2S,3S,4R)-2-Amino-1,3,4-octadecanetriol;(4R)-4-Hydroxysphinganine;D-ribo-Phytosphingosine CAS: 554-62-1 MF: C18H39NO3 MW: 317.51 EINECS: 439-210-6 Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Chiral Reagents;cosmestic;554-62-1 Mol File: 554-62-1.mol   PHYTOSPHINGOSINE Chemical Properties Melting point  102 °C Boiling point  483.7±40.0 °C(Predicted) density  0.983 vapor pressure  0.2Pa at 20℃ refractive index  9 ° (C=1, Pyridine) storage temp.  −20°C solubility  Soluble in Ethanol (up to 2 mg/ml). pka 11.91±0.45(Predicted) form  White to off-white solid. color  White Water Solubility  2.6mg/L at 20℃ Stability: Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month. InChIKey AERBNCYCJBRYDG-KSZLIROESA-N LogP 6.2 at 22℃   Safety Information WGK Germany  1 HS Code  29221990 MSDS Information   PHYTOSPHINGOSINE Usage And Synthesis Description Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330] Chemical Properties Off-White Solid Uses phytosphingosine is a sphingolipid that can improve the overall condition of skin and hair. Some sources site anti-microbial and anti-inflammatory properties. Research indicates similar activity to retinoic acid, in which case it may be particularly beneficial for aging and photo-aging skin. Uses Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation. Definition ChEBI: Phytosphingosine is a sphingoid, an amino alcohol and a triol. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a N-acyl-beta-D-galactosylphytosphingosine and a sphinganine. It is a conjugate base of a phytosphingosine(1+). Flammability and Explosibility Not classified Veterinary Drugs and Treatments Phytosphingosine is a unique topical antiseborrheic compound. It is in a class called ceramides which are waxy materials meant to meant to mimic the normal lipid composition of the stratum corneum. It may also have some antiinflammatory and antimicrobial properties. References 1) Fischer et al. (2012), Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria; Antimicrob. Agents Chemother., 56 1157 2) Fischer et al. (2013), Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage; Skin Pharmacol. Physiol., 26 36

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Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture high quality raw materials and refined ingredients which is widely used at different industries areas like Pharm & chemicals industry, functional active ingredients industry, nutritional Ingredients industry, health care products industry, cosmetics industry,  pharmaceutical and refined food, feed, oil industry, natural plant ingredients industries, agriculture industry etcs to provide top quality of GMP standards products. All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, agriculture raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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PHYTOSPHINGOSINE Basic information Product Name: PHYTOSPHINGOSINE Synonyms: PHYTOSPHINGOSINE;PHYTOSPHINGOSINE HYDROCHLORIDE;(2S, 3S, 4R)-2-AMINO-1,3,4-OCTADECANETRIOL 4-HYDROXYSPHINGANINE;4-HYDROXYSPHINGANINE;1,3,4-Octadecanetriol,2-amino-, (2S, 3S, 4R) -;(2S,3S,4R)-2-Amino-1,3,4-octadecanetriol;(4R)-4-Hydroxysphinganine;D-ribo-Phytosphingosine CAS: 554-62-1 MF: C18H39NO3 MW: 317.51 EINECS: 439-210-6 Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Amines;Chiral Reagents;cosmestic;554-62-1 Mol File: 554-62-1.mol   PHYTOSPHINGOSINE Chemical Properties Melting point  102 °C Boiling point  483.7±40.0 °C(Predicted) density  0.983 vapor pressure  0.2Pa at 20℃ refractive index  9 ° (C=1, Pyridine) storage temp.  −20°C solubility  Soluble in Ethanol (up to 2 mg/ml). pka 11.91±0.45(Predicted) form  White to off-white solid. color  White Water Solubility  2.6mg/L at 20℃ Stability: Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month. InChIKey AERBNCYCJBRYDG-KSZLIROESA-N LogP 6.2 at 22℃   Safety Information WGK Germany  1 HS Code  29221990 MSDS Information   PHYTOSPHINGOSINE Usage And Synthesis Description Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330] Chemical Properties Off-White Solid Uses phytosphingosine is a sphingolipid that can improve the overall condition of skin and hair. Some sources site anti-microbial and anti-inflammatory properties. Research indicates similar activity to retinoic acid, in which case it may be particularly beneficial for aging and photo-aging skin. Uses Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation. Definition ChEBI: Phytosphingosine is a sphingoid, an amino alcohol and a triol. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a N-acyl-beta-D-galactosylphytosphingosine and a sphinganine. It is a conjugate base of a phytosphingosine(1+). Flammability and Explosibility Not classified Veterinary Drugs and Treatments Phytosphingosine is a unique topical antiseborrheic compound. It is in a class called ceramides which are waxy materials meant to meant to mimic the normal lipid composition of the stratum corneum. It may also have some antiinflammatory and antimicrobial properties. References 1) Fischer et al. (2012), Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria; Antimicrob. Agents Chemother., 56 1157 2) Fischer et al. (2013), Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage; Skin Pharmacol. Physiol., 26 36