Glabridin Basic information |
Product Name: |
Glabridin |
Synonyms: |
1,3-Benzenediol, 4-(3,4-dihydro-8,8-diMethyl-2H,8H-benzo(1,2-b:3,4-b')dipyran-3-yl)-, (R)-;(R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol;4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl]-1,3-benzenediol;Glabridin, >=98%;Glabridin/Propylene Glycol;4-[(3R)-8,8-dimethyl-3,4-dihydro-2H,8H-pyrano[2,3-f]chromen-3-yl]benzene-1,3-diol;Glabridin/OIL SOLUBLE LICORICE(GLYCYRRHIZA) EXTRACT;professional manufacturer Glabridin 59870-68-7 |
CAS: |
59870-68-7 |
MF: |
C20H20O4 |
MW: |
324.37 |
EINECS: |
611-908-7 |
Product Categories: |
Miscellaneous Natural Products;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Natural Plant Extract |
Mol File: |
59870-68-7.mol |
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Glabridin Chemical Properties |
Melting point |
154~155℃ |
Boiling point |
518.6±50.0 °C(Predicted) |
density |
1.257±0.06 g/cm3(Predicted) |
Fp |
267℃ |
storage temp. |
room temp |
solubility |
DMSO: soluble5mg/mL, clear (warmed) |
pka |
9.66±0.40(Predicted) |
form |
powder |
color |
white to light brown |
BRN |
7141956 |
Stability: |
Hygroscopic |
InChIKey |
PMPYOYXFIHXBJI-ZDUSSCGKSA-N |
CAS DataBase Reference |
59870-68-7(CAS DataBase Reference) |
Safety Statements |
24/25 |
WGK Germany |
3 |
HS Code |
29329990 |
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Glabridin Usage And Synthesis |
Chemical Properties |
White to tan powder |
Uses |
Glabridin is a compound extracted from Licorice (root) shows properties that are cytotoxic, antimicrobial, estrogenic and anti-proliferative. |
Definition |
ChEBI: A member of the class of hydroxyisoflavans that is (R)-isoflavan substituted by hydroxy groups at positions 2' and 4' and a 2,2-dimethyl-2H-pyran group across positions 7 and 8 respectively. |
Biochem/physiol Actions |
Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9. |
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Glabridin Preparation Products And Raw materials |
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