China Largest Manufacturer factory sales D-MALIC ACID CAS 636-61-3 for 500MT/Year CAS NO.636-61-3

                                PRODUCT DETAILS                           

D(+)-Malic acid Basic information Product Name: D(+)-Malic acid Synonyms: Butanedioic acid, hydroxy-, (R)-;hydroxy-,(R)-Butanedioicacid;l(+)-malicaci;(R)-(+)-MALIC ACID;(R)-MALIC ACID;Malic Acid Impurity 3;(2R)-2-hydroxybutanedioate;(+)-D-MALIC ACID CAS: 636-61-3 MF: C4H6O5 MW: 134.09 EINECS: 211-262-2 Product Categories: Chiral Compound;Aliphatics;FINE Chemical & INTERMEDIATES;Food & Feed ADDITIVES;MalicAcidSeries;Chiral Reagents;chiral;API intermediates;All Aliphatics;Carboxylic Acids (Chiral);Chiral Building Blocks;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;CHIRAL CHEMICALS;Chiral chemicals Mol File: 636-61-3.mol   D(+)-Malic acid Chemical Properties Melting point  98-102 °C (lit.) alpha  2.2 º (c=3, H2O) Boiling point  167.16°C (rough estimate) density  1.60 refractive index  6.5 ° (C=10, Acetone) storage temp.  Store below +30°C. solubility  Soluble in methanol, ethanol, acetone, ether. pka 3.61±0.23(Predicted) form  Crystalline Powder color  White PH 2.2 (10g/l, H2O, 20℃) optical activity [α]20/D +28.0±2°, c = 5.5% in pyridine Water Solubility  soluble Merck  14,5707 BRN  1723540 CAS DataBase Reference 636-61-3(CAS DataBase Reference) NIST Chemistry Reference (r)-Hydroxybutanedioic acid(636-61-3)   Safety Information Hazard Codes  Xi Risk Statements  37/38-41-36/37/38 Safety Statements  26-36-37/39 WGK Germany  3 RTECS  ON7260000 HS Code  29181980 MSDS Information Provider Language D(+)-Malic acid English ACROS English SigmaAldrich English ALFA English   D(+)-Malic acid Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece Uses D-(+)-Malic acid used as an acidulant and flavoring agent, food additive. And it is also used in the place of the less sour citric acid in sour sweets. Uses D-(+)-Malic acid can be used: As a starting material for the enantioselective total synthesis of ( )-erinapyrone B. As a chiral organocatalyst in the synthesis of α-aminophosphonates from various aldehydes, aniline, and diethyl phosphite. Definition ChEBI: An optically active form of malic acid having (R)-configuration.   D(+)-Malic acid Preparation Products And Raw materials Raw materials Butanoic acid, 4,4,4-trichloro-3-hydroxy-, (R)- (9CI)-->MALEIC ACID-->(S)-2-CHLOROSUCCINIC ACID-->CHLOROSUCCINIC ACID-->L-Aspartic acid-->DL-Malic acid-->Oxobutanedioic acid-->Fumaric acid-->L-Asparagine-->L(+)-Tartaric acid-->Maleic acid-->L-(-)-Malic Acid Preparation Products (R)-(-)-3-Pyrrolidinol hydrochloride-->(R)-(+)-1-Benzyl-3-pyrrolidinol-->(R)-3-Hydroxypyrrolidine-->(S)-(+)-3-Quinuclidinol-->2-Butenoic acid, 4-hydroxy-2-methyl-, (E)- (9CI)-->DIISOPROPYL (R)-(+)-MALATE

                                                                       Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Our Factories production lines

                                                   Our Factories R&D ability

                        Our Factories warehouse 

                                                       Product information

D(+)-Malic acid Basic information Product Name: D(+)-Malic acid Synonyms: Butanedioic acid, hydroxy-, (R)-;hydroxy-,(R)-Butanedioicacid;l(+)-malicaci;(R)-(+)-MALIC ACID;(R)-MALIC ACID;Malic Acid Impurity 3;(2R)-2-hydroxybutanedioate;(+)-D-MALIC ACID CAS: 636-61-3 MF: C4H6O5 MW: 134.09 EINECS: 211-262-2 Product Categories: Chiral Compound;Aliphatics;FINE Chemical & INTERMEDIATES;Food & Feed ADDITIVES;MalicAcidSeries;Chiral Reagents;chiral;API intermediates;All Aliphatics;Carboxylic Acids (Chiral);Chiral Building Blocks;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;CHIRAL CHEMICALS;Chiral chemicals Mol File: 636-61-3.mol   D(+)-Malic acid Chemical Properties Melting point  98-102 °C (lit.) alpha  2.2 º (c=3, H2O) Boiling point  167.16°C (rough estimate) density  1.60 refractive index  6.5 ° (C=10, Acetone) storage temp.  Store below +30°C. solubility  Soluble in methanol, ethanol, acetone, ether. pka 3.61±0.23(Predicted) form  Crystalline Powder color  White PH 2.2 (10g/l, H2O, 20℃) optical activity [α]20/D +28.0±2°, c = 5.5% in pyridine Water Solubility  soluble Merck  14,5707 BRN  1723540 CAS DataBase Reference 636-61-3(CAS DataBase Reference) NIST Chemistry Reference (r)-Hydroxybutanedioic acid(636-61-3)   Safety Information Hazard Codes  Xi Risk Statements  37/38-41-36/37/38 Safety Statements  26-36-37/39 WGK Germany  3 RTECS  ON7260000 HS Code  29181980 MSDS Information Provider Language D(+)-Malic acid English ACROS English SigmaAldrich English ALFA English   D(+)-Malic acid Usage And Synthesis Chemical Properties white to light yellow crystal powde Uses The naturally occuring isomer is the L-form which has been found in apples and many other fruits and plants. Selective α-amino protecting reagent for amino acid derivatives. Versatile synthon for the preparation of chiral compounds including κ-opioid rece Uses D-(+)-Malic acid used as an acidulant and flavoring agent, food additive. And it is also used in the place of the less sour citric acid in sour sweets. Uses D-(+)-Malic acid can be used: As a starting material for the enantioselective total synthesis of ( )-erinapyrone B. As a chiral organocatalyst in the synthesis of α-aminophosphonates from various aldehydes, aniline, and diethyl phosphite. Definition ChEBI: An optically active form of malic acid having (R)-configuration.   D(+)-Malic acid Preparation Products And Raw materials Raw materials Butanoic acid, 4,4,4-trichloro-3-hydroxy-, (R)- (9CI)-->MALEIC ACID-->(S)-2-CHLOROSUCCINIC ACID-->CHLOROSUCCINIC ACID-->L-Aspartic acid-->DL-Malic acid-->Oxobutanedioic acid-->Fumaric acid-->L-Asparagine-->L(+)-Tartaric acid-->Maleic acid-->L-(-)-Malic Acid Preparation Products (R)-(-)-3-Pyrrolidinol hydrochloride-->(R)-(+)-1-Benzyl-3-pyrrolidinol-->(R)-3-Hydroxypyrrolidine-->(S)-(+)-3-Quinuclidinol-->2-Butenoic acid, 4-hydroxy-2-methyl-, (E)- (9CI)-->DIISOPROPYL (R)-(+)-MALATE