China Biggest Manufacturer factory sales D-Glucosamine Hydrochloride CAS 66-84-2 CAS NO.66-84-2

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D-Glucosamine hydrochloride Basic information Product Name: D-Glucosamine hydrochloride Synonyms: 2-DESOXY-2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOPYRANOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOSE HCL;2-AMINO-2-DEOXY-D-GLUCOSE HYDROCHLORIDE;D-(+)-GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D(+)-GLUCOSAMINE HYDROCHLORIDE CAS: 66-84-2 MF: C6H14ClNO5 MW: 215.63 EINECS: 200-638-1 Product Categories: Anilines, Aromatic Amines and Nitro Compounds;Inhibitors;Aminosugars;Biochemistry;Other APIs;Food additives;Glucose;Sugars;Nutritional Supplements;Dextrins、Sugar & Carbohydrates;Biological and chemical;chemical reagent;pharmaceutical intermediate;phytochemical;Food & Flavor Additives;Amines;Carbohydrates & Derivatives;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract Mol File: 66-84-2.mol   D-Glucosamine hydrochloride Chemical Properties Melting point  190-194 °C (dec.)(lit.) alpha  72.5 º (c=2, H2O, 5hrs.) refractive index  72 ° (C=1, H2O) storage temp.  2-8°C solubility  H2O: 0.1 g/mL, clear, colorless form  crystalline Water Solubility  soluble Merck  14,4458 BRN  4157370 Stability: Stable. Incompatible with strong oxidizing agents. Combustible. InChIKey QKPLRMLTKYXDST-LPRXMDNASA-N CAS DataBase Reference 66-84-2(CAS DataBase Reference) EPA Substance Registry System D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2)   Safety Information Hazard Codes  F,Xi,Xn Risk Statements  21-36/38-46-62-63 Safety Statements  24/25-53-36/37-26-25 WGK Germany  2 RTECS  LZ6665000 F  3-10 Hazard Note  Highly Flammable TSCA  Yes HS Code  29329985 MSDS Information Provider Language 2-Amino-2-deoxy-D-glucopyranose hydrochloride English SigmaAldrich English ACROS English   D-Glucosamine hydrochloride Usage And Synthesis Chemical Properties white powder Uses Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties. Uses glucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties. Uses Novel application of glucosamine is to prepare medical agent for treating vertigo. It is used as food ingredients and additives, raw material for anti cancer and antibiotic drugs. General Description Glucosamine, an amino sugar is generated form glucose and glutamine and is naturally produced in the body. Glucosamine, a endogenous amino monosaccharide is the major source of glucosamine-6-phosphate and n-acetylglucosamine. Biochem/physiol Actions Glucosamine is preferred as a nutritional supplement for individuals with osteoarthritis. It is used as a building block for the production of proteoglycans and glycosaminoglycans. Purification Methods Crystallise the hydrochloride from 3M HCl, water, and finally water/EtOH/acetone as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give  anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.]   D-Glucosamine hydrochloride Preparation Products And Raw materials Raw materials Potassium hydroxide-->Citric acid Preparation Products Fructosazine-->deoxyfructosazine-->1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE

                                      Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

D-Glucosamine hydrochloride Basic information Product Name: D-Glucosamine hydrochloride Synonyms: 2-DESOXY-2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-D-GLUCOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOPYRANOSE HYDROCHLORIDE;2-AMINO-2-DEOXY-D-GLUCOSE HCL;2-AMINO-2-DEOXY-D-GLUCOSE HYDROCHLORIDE;D-(+)-GLUCOSAMINE HCL;D-GLUCOSAMINE HCL;D(+)-GLUCOSAMINE HYDROCHLORIDE CAS: 66-84-2 MF: C6H14ClNO5 MW: 215.63 EINECS: 200-638-1 Product Categories: Anilines, Aromatic Amines and Nitro Compounds;Inhibitors;Aminosugars;Biochemistry;Other APIs;Food additives;Glucose;Sugars;Nutritional Supplements;Dextrins、Sugar & Carbohydrates;Biological and chemical;chemical reagent;pharmaceutical intermediate;phytochemical;Food & Flavor Additives;Amines;Carbohydrates & Derivatives;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract Mol File: 66-84-2.mol   D-Glucosamine hydrochloride Chemical Properties Melting point  190-194 °C (dec.)(lit.) alpha  72.5 º (c=2, H2O, 5hrs.) refractive index  72 ° (C=1, H2O) storage temp.  2-8°C solubility  H2O: 0.1 g/mL, clear, colorless form  crystalline Water Solubility  soluble Merck  14,4458 BRN  4157370 Stability: Stable. Incompatible with strong oxidizing agents. Combustible. InChIKey QKPLRMLTKYXDST-LPRXMDNASA-N CAS DataBase Reference 66-84-2(CAS DataBase Reference) EPA Substance Registry System D-Glucose, 2-amino-2-deoxy-, hydrochloride (66-84-2)   Safety Information Hazard Codes  F,Xi,Xn Risk Statements  21-36/38-46-62-63 Safety Statements  24/25-53-36/37-26-25 WGK Germany  2 RTECS  LZ6665000 F  3-10 Hazard Note  Highly Flammable TSCA  Yes HS Code  29329985 MSDS Information Provider Language 2-Amino-2-deoxy-D-glucopyranose hydrochloride English SigmaAldrich English ACROS English   D-Glucosamine hydrochloride Usage And Synthesis Chemical Properties white powder Uses Novel application of D-Glucosamine hydrochloride to prepare medical agent for treating vertigo. Found in chitin, in mucoproteins, and in mucopolysaccharides. Antiarthritic. Recent studies show that its chondroprotective activity is related to its antiapoptic properties. Uses glucosamine hydrochloride (glucosamine HCl) is used to adjust the pH of a formulation. It also has anti-static and hair-conditioning properties. Uses Novel application of glucosamine is to prepare medical agent for treating vertigo. It is used as food ingredients and additives, raw material for anti cancer and antibiotic drugs. General Description Glucosamine, an amino sugar is generated form glucose and glutamine and is naturally produced in the body. Glucosamine, a endogenous amino monosaccharide is the major source of glucosamine-6-phosphate and n-acetylglucosamine. Biochem/physiol Actions Glucosamine is preferred as a nutritional supplement for individuals with osteoarthritis. It is used as a building block for the production of proteoglycans and glycosaminoglycans. Purification Methods Crystallise the hydrochloride from 3M HCl, water, and finally water/EtOH/acetone as for galactosamine hydrochloride. [Purchase & Braun Org Synth 26 36 1946, Stacey & Webber Methods in Carbohydrate Chemistry I 228 1962, Academic Press.] The salt has also been purified by dissolving in the minimum volume of boiling H2O (charcoal), filtering and adding a large excess of 95% EtOH (~4 volumes) and stirring vigorously for several hours. Collect the crystals after 4-6hours to give  anomer which mutarotates ] D +100o to +72o (equilibrium, c 1, H2O). A large amount of the -anomer stays in solution. This can be precipitated from the filtrate by adding excess Et2O. The mixture of -plus -anomers has [] D +68.8o (c 4.75, H2O, mutarotating to +70.1o)[Leaback Biochemical Preparations 10 118 1963]. Note that if Et2NH is used instead of Et3N, conversion to the -anomer can be complete (see above). [Stacey et al. Methods in Carbohydrate Chemistry I 3061962, Academic Press; Beilstein 4 IV 2018.]   D-Glucosamine hydrochloride Preparation Products And Raw materials Raw materials Potassium hydroxide-->Citric acid Preparation Products Fructosazine-->deoxyfructosazine-->1-[4-(1,2,3,4-TETRAHYDROXYBUTYL)-1H-IMIDAZOL-2-YL]ETHANONE