China Biggest Factory manufacturer supply Piroctone Olamine CAS NO.68890-66-4

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Piroctone olamine Basic information Description Appearance Solubility Toxicity Product Name: Piroctone olamine Synonyms: 2(1H)-Pyridinone,1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-,compd.with2-aminoethanol(1:1);4,4-trimethylpentyl)-1-hydroxy-4-methyl-6-(compd.with2-2(1h)-pyridinon;octopiroxolamine;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1h)-pyridinoncompd.with2-aminoethanol(1:1);Hydroxyl pyrazole ketones;1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine;1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl);-one compound with 2-aminoethanol (1:1) CAS: 68890-66-4 MF: C16H30N2O3 MW: 298.43 EINECS: 272-574-2 Product Categories: bacteriostatic and fungistatic;ARAMINE;OLED materials,pharm chemical,electronic;PP;68890-66-4 Mol File: 68890-66-4.mol   Piroctone olamine Chemical Properties Melting point  134.0 to 138.0 °C storage temp.  Inert atmosphere,2-8°C solubility  Chloroform (Slightly, Sonicated), Methanol (Slightly) form  neat color  White to Off-White Merck  14,7502 InChIKey BTSZTGGZJQFALU-UHFFFAOYSA-N CAS DataBase Reference 68890-66-4(CAS DataBase Reference)   Safety Information WGK Germany  2 RTECS  UU7786150 HS Code  2933399090 MSDS Information   Piroctone olamine Usage And Synthesis Description Piroctone olamine (INN; also known as piroctone ethanolamine; brand name Octopirox) is a compound sometimes used in the treatment of fungal infections.Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone. Appearance White or slightly yellow crystalline powder. Solubility Freely soluble in 10% ethanol in water; soluble in solution containing surfactants in water or in 1%-10% ethanol; slightly soluble in water and in oil. The solubility in water varies by pH value, and is a litter larger in neutral or weak basic solution than in acid solution. Toxicity Acute toxicity : Acute oral LD50 –rat 8100mg/kg, practically nontoxic. Subchronic toxicity : NOEL: 100mg//kg/d (rat, orally, 3 months). Chronic toxicity and carcinogencity : Negative. Mutagenicity : Negative. Irritation to skin and eye : Very low. Uses Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma. Uses Piroctone Olamine is an anti-dandruff agent used in shampoo formulations. Definition ChEBI: An organoammonium salt that is the ethanolamine salt of piroctone. Brand name Octopirox (Hoechst AG, Germany).   Piroctone olamine Preparation Products And Raw materials Raw materials 3,5,5-Trimethylhexanoyl chloride-->Methyl 3-methyl-2-butenoat

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Piroctone olamine Basic information Description Appearance Solubility Toxicity Product Name: Piroctone olamine Synonyms: 2(1H)-Pyridinone,1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-,compd.with2-aminoethanol(1:1);4,4-trimethylpentyl)-1-hydroxy-4-methyl-6-(compd.with2-2(1h)-pyridinon;octopiroxolamine;1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2(1h)-pyridinoncompd.with2-aminoethanol(1:1);Hydroxyl pyrazole ketones;1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon monoethanolamine;1-Hydroxy-4-methyl-6-(2,4,4-trimethylpentyl);-one compound with 2-aminoethanol (1:1) CAS: 68890-66-4 MF: C16H30N2O3 MW: 298.43 EINECS: 272-574-2 Product Categories: bacteriostatic and fungistatic;ARAMINE;OLED materials,pharm chemical,electronic;PP;68890-66-4 Mol File: 68890-66-4.mol   Piroctone olamine Chemical Properties Melting point  134.0 to 138.0 °C storage temp.  Inert atmosphere,2-8°C solubility  Chloroform (Slightly, Sonicated), Methanol (Slightly) form  neat color  White to Off-White Merck  14,7502 InChIKey BTSZTGGZJQFALU-UHFFFAOYSA-N CAS DataBase Reference 68890-66-4(CAS DataBase Reference)   Safety Information WGK Germany  2 RTECS  UU7786150 HS Code  2933399090 MSDS Information   Piroctone olamine Usage And Synthesis Description Piroctone olamine (INN; also known as piroctone ethanolamine; brand name Octopirox) is a compound sometimes used in the treatment of fungal infections.Piroctone olamine is the ethanolamine salt of the hydroxamic acid derivative piroctone. Appearance White or slightly yellow crystalline powder. Solubility Freely soluble in 10% ethanol in water; soluble in solution containing surfactants in water or in 1%-10% ethanol; slightly soluble in water and in oil. The solubility in water varies by pH value, and is a litter larger in neutral or weak basic solution than in acid solution. Toxicity Acute toxicity : Acute oral LD50 –rat 8100mg/kg, practically nontoxic. Subchronic toxicity : NOEL: 100mg//kg/d (rat, orally, 3 months). Chronic toxicity and carcinogencity : Negative. Mutagenicity : Negative. Irritation to skin and eye : Very low. Uses Piroctone olamine is used in combination with other substances as a part of shampoo effectively reduced the amount of dandruff and, at the same time, provided hair conditioning advantages. Recently was shown, that piroctone olamine could induce apoptosis and possessed a significant in vivo effect against myeloma. Uses Piroctone Olamine is an anti-dandruff agent used in shampoo formulations. Definition ChEBI: An organoammonium salt that is the ethanolamine salt of piroctone. Brand name Octopirox (Hoechst AG, Germany).   Piroctone olamine Preparation Products And Raw materials Raw materials 3,5,5-Trimethylhexanoyl chloride-->Methyl 3-methyl-2-butenoat