China Largest Manufacturer factory sales D(-)-Glutamic acid CAS 6893-26-1 CAS NO.6893-26-1

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D(-)-Glutamic acid Basic information Product Name: D(-)-Glutamic acid Synonyms: (2R)-2-Aminoglutaric acid;D-α-AMinoglutaric acid;D-1-AMinopropane-1,3-dicarboxylic acid;D(-)-GlutaMic acid, 99+% 25GR;D(-)-GlutaMic acid, 99+% 5GR;(2R)-GlutaMic Acid;NSC 77686;D-Glutaminic acid CAS: 6893-26-1 MF: C5H9NO4 MW: 147.13 EINECS: 230-000-8 Product Categories: amino acid;Glutamate receptor;Amino ACIDS SERIES;Glutamic acid [Glu, E];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Nutritional Supplements;Amino Acids Mol File: 6893-26-1.mol   D(-)-Glutamic acid Chemical Properties Melting point  200-202 °C (subl.)(lit.) alpha  -31.3 º (c=10, 2 N HCl) Boiling point  267.21°C (rough estimate) density  1.5380 refractive index  1.4210 (estimate) storage temp.  Keep in dark place,Sealed in dry,Room Temperature solubility  Water (Slightly) form  Powder pka pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C) color  White to off-white Water Solubility  7 g/L (20 ºC) Merck  14,4469 BRN  1723800 InChIKey WHUUTDBJXJRKMK-GSVOUGTGSA-N CAS DataBase Reference 6893-26-1(CAS DataBase Reference) NIST Chemistry Reference D-Glutamic acid(6893-26-1) EPA Substance Registry System D-Glutamic acid (6893-26-1)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  3 F  10 TSCA  Yes HS Code  29224200 MSDS Information Provider Language D-2-Aminoglutaric acid English ACROS English SigmaAldrich English ALFA English   D(-)-Glutamic acid Usage And Synthesis Chemical Properties White cryst. powder Uses D-Glutamic Acid is the unnatural (R)-enantiomer of Glutamic Acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. Glutamic Acid is also a key molecule in cellular metabolism. Uses D-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods. Uses D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors. Definition ChEBI: An optically active form of glutamic acid having D-configuration. General Description D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan. Biological Activity Excitatory amino acid acting at NMDA receptors; less active than the L-isomer. Biochem/physiol Actions Unnatural isomer of glutamic acid.   D(-)-Glutamic acid Preparation Products And Raw materials Raw materials DL-Glutamic acid-->4-methylsulfanyl-2-oxo-butanoic acid-->3-(4-Imidazolyl)-2-oxopropionic acid-->D-Norleucine-->D(-)-Norvaline-->D-Histidine-->D-Glutamine-->D-Methionine-->2-Oxopentanoic acid-->3-METHYL-2-OXOBUTYRIC ACIDDISCONTINUED-->2-oxohexanoic acid-->D-Threonine-->L-Glutamic acid Preparation Products 5-Hydroxymethylpyrrolidin-2-one-->D-Pyroglutamic acid-->2-Oxobutyric acid-->4-Methyl-2-oxovaleric acid-->2-Ketoglutaric acid-->L-Leucine

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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D(-)-Glutamic acid Basic information Product Name: D(-)-Glutamic acid Synonyms: (2R)-2-Aminoglutaric acid;D-α-AMinoglutaric acid;D-1-AMinopropane-1,3-dicarboxylic acid;D(-)-GlutaMic acid, 99+% 25GR;D(-)-GlutaMic acid, 99+% 5GR;(2R)-GlutaMic Acid;NSC 77686;D-Glutaminic acid CAS: 6893-26-1 MF: C5H9NO4 MW: 147.13 EINECS: 230-000-8 Product Categories: amino acid;Glutamate receptor;Amino ACIDS SERIES;Glutamic acid [Glu, E];Amino Acids and Derivatives;alpha-Amino Acids;Amino Acids;Biochemistry;for Resolution of Bases;Optical Resolution;Synthetic Organic Chemistry;Nutritional Supplements;Amino Acids Mol File: 6893-26-1.mol   D(-)-Glutamic acid Chemical Properties Melting point  200-202 °C (subl.)(lit.) alpha  -31.3 º (c=10, 2 N HCl) Boiling point  267.21°C (rough estimate) density  1.5380 refractive index  1.4210 (estimate) storage temp.  Keep in dark place,Sealed in dry,Room Temperature solubility  Water (Slightly) form  Powder pka pK1:2.162(＋1);pK2:4.272(0);pK3:9.358(－1) (25°C) color  White to off-white Water Solubility  7 g/L (20 ºC) Merck  14,4469 BRN  1723800 InChIKey WHUUTDBJXJRKMK-GSVOUGTGSA-N CAS DataBase Reference 6893-26-1(CAS DataBase Reference) NIST Chemistry Reference D-Glutamic acid(6893-26-1) EPA Substance Registry System D-Glutamic acid (6893-26-1)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  24/25-36-26 WGK Germany  3 F  10 TSCA  Yes HS Code  29224200 MSDS Information Provider Language D-2-Aminoglutaric acid English ACROS English SigmaAldrich English ALFA English   D(-)-Glutamic acid Usage And Synthesis Chemical Properties White cryst. powder Uses D-Glutamic Acid is the unnatural (R)-enantiomer of Glutamic Acid, a non-essential amino acid. Its salt form (glutamate) is an important neurotransmitter that plays a key role in long-term potentiation and is important for learning and memory. Glutamic Acid is also a key molecule in cellular metabolism. Uses D-Glutamic acid acts as a superior to alpha ketoglutarate. It helps in the growth of Lactobacillus arabinosus. It can inhibit the IgE binding to peanut allergens. It is widely used in pharmaceuticals and foods. Uses D-glutamic acid is suitable for use in the structure-affinity relationship (SAR)-study of GR (glutamate racemase) enzyme and its inhibitors. Definition ChEBI: An optically active form of glutamic acid having D-configuration. General Description D-Glutamic acid is an essential constituent of the bacterial peptidoglycan structure. It is added to UDP-N-acetylmuramyl-L-alanine (UDP-MurNAc-L-alanine) by the enzyme D-glutamic acid-adding enzyme (murD). This is, then, incorporated into the peptidoglycan precursor. Peptidoglycan makes up the cell walls of Gram-positive and -negative bacteria. The conversion of L-glutamate to D-glutamate by glutamate racemase (GR) enzyme is an essential step in the synthesis of peptidoglycan. Biological Activity Excitatory amino acid acting at NMDA receptors; less active than the L-isomer. Biochem/physiol Actions Unnatural isomer of glutamic acid.   D(-)-Glutamic acid Preparation Products And Raw materials Raw materials DL-Glutamic acid-->4-methylsulfanyl-2-oxo-butanoic acid-->3-(4-Imidazolyl)-2-oxopropionic acid-->D-Norleucine-->D(-)-Norvaline-->D-Histidine-->D-Glutamine-->D-Methionine-->2-Oxopentanoic acid-->3-METHYL-2-OXOBUTYRIC ACIDDISCONTINUED-->2-oxohexanoic acid-->D-Threonine-->L-Glutamic acid Preparation Products 5-Hydroxymethylpyrrolidin-2-one-->D-Pyroglutamic acid-->2-Oxobutyric acid-->4-Methyl-2-oxovaleric acid-->2-Ketoglutaric acid-->L-Leucine