China Largest Manufacturer factory sales L-Arginine L-aspartate CAS 7675-83-4 CAS NO.7675-83-4

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L-Arginine L-aspartate Basic information Product Name: L-Arginine L-aspartate Synonyms: arginineaspartate;l-asparticacid,compd.withl-arginine(1:1);L-ARG L-ASP;L-ARGININE L-ASPARTATE;L-ARGININE L-ASPARATE;L-ARGININE1-ASPARTATE;L-Arginine¤L-aspartic acid;L-aspartic acid, compound with L-arginine (1:1) CAS: 7675-83-4 MF: C10H21N5O6 MW: 307.3 EINECS: 231-656-8 Product Categories: amino acid;Amino Acids;Nutritional Supplements Mol File: 7675-83-4.mol   L-Arginine L-aspartate Chemical Properties Melting point  220-221 °C storage temp.  2-8°C solubility  Very soluble in water, practically insoluble in alcohol and in methylene chloride. form  neat color  White to Off-White Stability: Hygroscopic CAS DataBase Reference 7675-83-4(CAS DataBase Reference) EPA Substance Registry System Arginine aspartate (7675-83-4)   Safety Information MSDS Information   L-Arginine L-aspartate Usage And Synthesis Chemical Properties White or almost white granules or powder. Originator Arginine aspartate,Microbase Biotech Co., Ltd. Uses Amino acid; nutrient. Uses L-Arginine L-Aspartate is used in investigation of the metabolic profiles of human breast cancer. Manufacturing Process 1000 ml of polystyrene-trimethylbenzylammonium ion exchange resin were converted into the chloride form by passing aqueous hydrochloride acid over the resin. The resin was washed with distilled water to remove all traces of passed over the resin. A 10% excess of the calcium aspartate solution over the theoretical ion-exchange capacity of the resin was used and the resin was then washed with water until the wash water was free of chloride ions. At the end of this treatment, the resin was in the aspartic acid form. An aqueous solution containing 168.56 g of calcium aspartate and 49.44 g of arginine dihydrochloride per litre was prepared, and this solution was passed slowly over the aspartic acid form resin. The effluent liquid was collected in fractions of 200 ml, then of 100 ml, and towards the end, in fractions of 50 ml. After about 1000 ml of eluate had been collected, the succeeding fractions were examined very carefully for the presence of chloride ion. All the eluate fractions prior to the first one containing traces of chloride, i.e. all the chloride-free eluate fractions, were combined, the combined chloride eluates amounted to about 1300 ml. The arginine present was determined by Sakaguchis method and the total nitrogen in the combined eluates was also determined. These determinations showed that the eluates contained from 270 to 300 g of arginine aspartare per litre. The combined eluates were evaporated to a volume of about 500 ml and allowed to crystallize at a low temperature (0°-4°C). After seeding with a crystal of arginine aspartate, colourless crystals were obtained, they were filtered off, washed with aqueous ethanol, and then dried. About 210 g, i.e. 70% of the theoretical yield, of crystals having a decomposition point of 220°C was obtained. The mother liquor from the first crystallization was evaporated down to a volume of about 150 ml. Ethanol was added to the solution until cloudiness which persisted was obtained, the solution was cooled to 0°C and a second crop of crystals was obtained. The size of this second crop was increased by adding further ethanol after the major portion of the second crop had crystallized and allowing the mixture to stand for 48 hours at 0°C. After separation, the second fraction consisted of 75 g of a crystalline mass which had the same physico-chemical and chemical properties as the main fraction. Therapeutic Function Tonic, Stimulant, Hepatoprotectant Biochem/physiol Actions Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.   L-Arginine L-aspartate Preparation Products And Raw materials Raw materials CALCIUM-->ASPARTATE CALCIUM

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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L-Arginine L-aspartate Basic information Product Name: L-Arginine L-aspartate Synonyms: arginineaspartate;l-asparticacid,compd.withl-arginine(1:1);L-ARG L-ASP;L-ARGININE L-ASPARTATE;L-ARGININE L-ASPARATE;L-ARGININE1-ASPARTATE;L-Arginine¤L-aspartic acid;L-aspartic acid, compound with L-arginine (1:1) CAS: 7675-83-4 MF: C10H21N5O6 MW: 307.3 EINECS: 231-656-8 Product Categories: amino acid;Amino Acids;Nutritional Supplements Mol File: 7675-83-4.mol   L-Arginine L-aspartate Chemical Properties Melting point  220-221 °C storage temp.  2-8°C solubility  Very soluble in water, practically insoluble in alcohol and in methylene chloride. form  neat color  White to Off-White Stability: Hygroscopic CAS DataBase Reference 7675-83-4(CAS DataBase Reference) EPA Substance Registry System Arginine aspartate (7675-83-4)   Safety Information MSDS Information   L-Arginine L-aspartate Usage And Synthesis Chemical Properties White or almost white granules or powder. Originator Arginine aspartate,Microbase Biotech Co., Ltd. Uses Amino acid; nutrient. Uses L-Arginine L-Aspartate is used in investigation of the metabolic profiles of human breast cancer. Manufacturing Process 1000 ml of polystyrene-trimethylbenzylammonium ion exchange resin were converted into the chloride form by passing aqueous hydrochloride acid over the resin. The resin was washed with distilled water to remove all traces of passed over the resin. A 10% excess of the calcium aspartate solution over the theoretical ion-exchange capacity of the resin was used and the resin was then washed with water until the wash water was free of chloride ions. At the end of this treatment, the resin was in the aspartic acid form. An aqueous solution containing 168.56 g of calcium aspartate and 49.44 g of arginine dihydrochloride per litre was prepared, and this solution was passed slowly over the aspartic acid form resin. The effluent liquid was collected in fractions of 200 ml, then of 100 ml, and towards the end, in fractions of 50 ml. After about 1000 ml of eluate had been collected, the succeeding fractions were examined very carefully for the presence of chloride ion. All the eluate fractions prior to the first one containing traces of chloride, i.e. all the chloride-free eluate fractions, were combined, the combined chloride eluates amounted to about 1300 ml. The arginine present was determined by Sakaguchis method and the total nitrogen in the combined eluates was also determined. These determinations showed that the eluates contained from 270 to 300 g of arginine aspartare per litre. The combined eluates were evaporated to a volume of about 500 ml and allowed to crystallize at a low temperature (0°-4°C). After seeding with a crystal of arginine aspartate, colourless crystals were obtained, they were filtered off, washed with aqueous ethanol, and then dried. About 210 g, i.e. 70% of the theoretical yield, of crystals having a decomposition point of 220°C was obtained. The mother liquor from the first crystallization was evaporated down to a volume of about 150 ml. Ethanol was added to the solution until cloudiness which persisted was obtained, the solution was cooled to 0°C and a second crop of crystals was obtained. The size of this second crop was increased by adding further ethanol after the major portion of the second crop had crystallized and allowing the mixture to stand for 48 hours at 0°C. After separation, the second fraction consisted of 75 g of a crystalline mass which had the same physico-chemical and chemical properties as the main fraction. Therapeutic Function Tonic, Stimulant, Hepatoprotectant Biochem/physiol Actions Substrate of nitric oxide synthase, which is converted to citrulline and nitric oxide (NO). Induces insulin release by a nitric oxide-dependent mechanism.   L-Arginine L-aspartate Preparation Products And Raw materials Raw materials CALCIUM-->ASPARTATE CALCIUM