China Biggest Factory manufacturer supply Anhydrous Lanolin USP 2000MT/Year CAS NO.8006-54-0

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

Product information

Lanolin Basic information Description Benefits Product Name: Lanolin Synonyms: WOOL FAT;ADEPS LANAE;BASE, LANOLIN OINTMENT, HYDRATED, HYDROPHILIC;BASE, LANOLIN OIL AND CARBAMIDE OINTMENT, HYDRATED, HYDROPHILIC;HYPOALLERGENIC LANOLIN;LANOLIN DEHYDRATE;LANOLIN OIL;LANOLIN HYDROUS CAS: 8006-54-0 MF: N/A MW: 0 EINECS: 232-348-6 Product Categories: Steroids;Cosmetics;8006-54-0 Mol File: Mol File   Lanolin Chemical Properties Melting point  38-40 °C density  0.932-0.945 g/cm3(Temp: 15 °C) Fp  209 °C storage temp.  Sealed in dry,Room Temperature solubility  chloroform: 0.1 g/mL, clear to faintly turbid (<29 NTU), strongly yellow-green form  Adhering Crystals or Powder color  White to yellow Water Solubility  Soluble in ether, petroleum ether, chloroform and petroleum benzene. Sparingly soluble in ethanol. Insoluble in water. Merck  14,5358 EPA Substance Registry System Lanolin (8006-54-0)   Safety Information Safety Statements  24/25 WGK Germany  1 RTECS  OE3201000 Autoignition Temperature 833 °F TSCA  Yes HS Code  15050000 Hazardous Substances Data 8006-54-0(Hazardous Substances Data) MSDS Information Provider Language Lanolin English SigmaAldrich English ACROS English ALFA English   Lanolin Usage And Synthesis Description Lanolin oil is a secretion from sheep’s skin. It’s similar to human sebum, an oil secreted by the sebaceous glands that you may notice particularly on your nose. Unlike sebum, lanolin contains no triglycerides. Lanolin is sometimes referred to as “wool fat,” but the term is misleading because it lacks triglycerides needed to be considered a fat. The purpose of lanolin is to condition and protect sheep’s wool. This conditioning property is why the substance is now widely used in human cosmetics, skin care, and hair products. Lanolin oil is extracted by putting sheep’s wool through a centrifuge machine that separates the oil from other chemicals and debris. The process is performed after the sheep is sheared so the extraction of lanolin causes no harm to sheep. Benefits Lanolin is a very good ingredient for someone with dry skin, though it can be a problem for someone with oily or breakout-prone skin. Also, as an animal-derived ingredient, lanolin is sometimes viewed as less favorable in comparison to synthetic or plant-derived alternatives.   Chemical Properties yellow wax Chemical Properties Lanolin is a pale yellow-colored, unctuous, waxy substance with a faint, characteristic odor. Melted lanolin is a clear or almost clear, yellow liquid. Uses lanolin (hydrogenated) is a lanolin derivative. Uses lanolin is an emollient with moisturizing properties and an emulsifier with high water–absorption capabilities. It forms a network on the skin’s surface rather than a film, as is the case with petrolatum (Vaseline.). While long-term studies associate a low incidence of allergic reactions to lanolin, it remains a controversial ingredient based on a potential pesticide content and potential comedogenicity. There is a move among high-quality lanolin manufacturers to produce low-pesticide lanolin and among high-quality cosmetic formulators and manufacturers to use the purist form available. Lanolin’s comedogenicity potential is increasingly debated as some researchers believe it to be inaccurate, especially when lanolin is used in an emulsion. Lanolin is a sheep’s wool derivative formed by a fat-like viscous secretion of the sheep’s sebaceous glands. Some consider it a natural wax. Uses lanolin wax is a lanolin derivative. This is the semisolid fraction of lanolin obtained by physical means from whole lanolin. Production Methods Lanolin is a naturally occurring wax-like material obtained from the wool of sheep, Ovis aries Linne′ (Fam. Bovidae). Crude lanolin is saponified with a weak alkali and the resultant saponified fat emulsion is centrifuged to remove the aqueous phase. The aqueous phase contains a soap solution from which, on standing, a layer of partially purified lanolin separates. This material is then further refined by treatment with calcium chloride, followed by fusion with unslaked lime to dehydrate the lanolin. The lanolin is finally extracted with acetone and the solvent is removed by distillation. Definition A yellowish viscous substance obtained from wool fat. It contains cholesterol and terpene compounds, and is used in cosmetics, in ointments, and in treating leather. Definition lanolin: An emulsion of purified wool fat in water, containing cholesteroland certain terpene alcoholsand esters. It is used in cosmetics. Pharmaceutical Applications Lanolin is widely used in topical pharmaceutical formulations and cosmetics. Lanolin may be used as a hydrophobic vehicle and in the preparation of water-in-oil creams and ointments. When mixed with suitable vegetable oils or with soft paraffin, it produces emollient creams that penetrate the skin and hence facilitate the absorption of drugs. Lanolin mixes with about twice its own weight of water, without separation, to produce stable emulsions that do not readily become rancid on storage. Safety Lanolin is widely used in cosmetics and a variety of topical pharmaceutical formulations. Although generally regarded as a nontoxic and nonirritant material, lanolin and lanolin derivatives are associated with skin hypersensitivity reactions, and the use of lanolin in subjects with known sensitivity should be avoided. Other reports suggest that ‘sensitivity’ arises from false positives in patch testing.However, skin hypersensitivity is relatively uncommon; the incidence of hypersensitivity to lanolin in the general population is estimated to be around 5 per million. Sensitivity is thought to be associated with the content of free fatty alcohols present in lanolin products rather than the total alcohol content.The safety of pesticide residues in lanolin products has also been of concern. However, highly refined ‘hypoallergenic’ grades of lanolin and grades with low pesticide residues are commercially available. storage Lanolin may gradually undergo autoxidation during storage. To inhibit this process, the inclusion of butylated hydroxytoluene is permitted as an antioxidant. Exposure to excessive or prolonged heating may cause anhydrous lanolin to darken in color and develop a strong rancidlike odor. However, lanolin may be sterilized by dry heat at 150°C. Ophthalmic ointments containing lanolin may be sterilized by filtration or by exposure to gamma irradiation. Incompatibilities Lanolin may contain prooxidants, which may affect the stability of certain active drugs. Regulatory Status Included in the FDA Inactive Ingredients Database (ophthalmic, otic, topical, and vaginal preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Lanolin Preparation Products And Raw materials Raw materials FUMING SULFURIC ACID-->Water-->Benzonitrile-->laundry soap