China Biggest Manufacturer factory sales 2,5-Di-tert-butylhydroquinone(DTBHQ) CAS 88-58-4 CAS NO.88-58-4

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2,5-Di-tert-butylhydroquinone Basic information Product Name: 2,5-Di-tert-butylhydroquinone Synonyms: BHQ;DBHQ;Dibutylhydroquinone;DI-TERT-BUTYL HYDROQUINONE(2,5-);DI-T-BUTYLHYDROQUINONE;2,5-Di-tert-butylquinol;Di-Tertiary Butylhydroquinone;2,5-DI-TERT-BUTYL-1,4-HYDROQUINONE (DBHQ) CAS: 88-58-4 MF: C14H22O2 MW: 222.32 EINECS: 201-841-8 Product Categories: Signalling;Organic Building Blocks;Anthraquinones, Hydroquinones and Quinones;Oxygen Compounds;Polyols;Calcium signaling;Industrial/Fine Chemicals Mol File: 88-58-4.mol   2,5-Di-tert-butylhydroquinone Chemical Properties Melting point  216-218 °C(lit.) Boiling point  321°C density  1,07 g/cm3 refractive index  1.4576 (estimate) Fp  216 °C storage temp.  Store below +30°C. pka 11.89±0.23(Predicted) form  Crystalline Powder color  Light beige to pink-beige BRN  2049542 Stability: Stable. Incompatible with oxidizing agents. CAS DataBase Reference 88-58-4(CAS DataBase Reference) NIST Chemistry Reference 1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)-(88-58-4) EPA Substance Registry System 1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)- (88-58-4)   Safety Information Hazard Codes  Xi,Xn Risk Statements  36/37/38-22 Safety Statements  26-24/25 WGK Germany  3 RTECS  MX5160000 Autoignition Temperature 790 °F Hazard Note  Irritant TSCA  Yes HS Code  29072900 MSDS Information Provider Language Dibutylhydroquinone English ACROS English SigmaAldrich English ALFA English   2,5-Di-tert-butylhydroquinone Usage And Synthesis Chemical Properties cream or pale brown solid Uses 2,5-Di-tert-butylhydroquinone is the oxidation substrate used to measure the catalytic activity of the copper(II) enzyme-like catalysts. Definition ChEBI: A member of the class of hydroquinones that is benzene-1,4-diol substituted by tert-butyl groups at position 2 and 5. General Description Mobilizes Ca2+ specifically from the Ins(1,4,5)P3-sensitive Ca2+ stores by inhibiting microsomal and sarcoplasmic reticulum Ca2+-ATPase activity. Does not affect mitochondrial Ca2+ fluxes or plasma membrane Ca2+/Mg2+ ATPase activity. Useful for the study of endomembrane Ca2+ stores and plasma membrane Ca2+ permeability pathways. Biological Activity A selective inhibitor of endoplasmic reticulum Ca 2+ -ATPase. Biochem/physiol Actions 2,5-Di-tert-butylhydroquinone specifically inhibits the sarcoplasmic reticulum (SR) Ca2+ uptake in the rat ventricle. Purification Methods Crystallise the hydroquinone from *C6H6 or AcOH. [Beilstein 6 III 4741.]   2,5-Di-tert-butylhydroquinone Preparation Products And Raw materials Raw materials Hydroquinone-->ISOBUTYLENE-->1,4-Benzenediol, 2-(1,1-dimethylethyl)-5-(2-propen-1-yl)--->2,5-Di-tert-butyl-1,4-benzoquinone-->Allyltributyltin Preparation Products 6-BROMO-1H-INDOLE-2-CARBALDEHYDE-->(6-BROMO-1H-INDOL-2-YL)METHANOL-->6-Bromoindole-2-carboxylic acid-->Ethyl 6-bromoindole-2-carboxylate-->tert-Butylhydroquinone-->2,6-di-tert-butylhydroquinone-->Phenyl-t-butylether

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

2,5-Di-tert-butylhydroquinone Basic information Product Name: 2,5-Di-tert-butylhydroquinone Synonyms: BHQ;DBHQ;Dibutylhydroquinone;DI-TERT-BUTYL HYDROQUINONE(2,5-);DI-T-BUTYLHYDROQUINONE;2,5-Di-tert-butylquinol;Di-Tertiary Butylhydroquinone;2,5-DI-TERT-BUTYL-1,4-HYDROQUINONE (DBHQ) CAS: 88-58-4 MF: C14H22O2 MW: 222.32 EINECS: 201-841-8 Product Categories: Signalling;Organic Building Blocks;Anthraquinones, Hydroquinones and Quinones;Oxygen Compounds;Polyols;Calcium signaling;Industrial/Fine Chemicals Mol File: 88-58-4.mol   2,5-Di-tert-butylhydroquinone Chemical Properties Melting point  216-218 °C(lit.) Boiling point  321°C density  1,07 g/cm3 refractive index  1.4576 (estimate) Fp  216 °C storage temp.  Store below +30°C. pka 11.89±0.23(Predicted) form  Crystalline Powder color  Light beige to pink-beige BRN  2049542 Stability: Stable. Incompatible with oxidizing agents. CAS DataBase Reference 88-58-4(CAS DataBase Reference) NIST Chemistry Reference 1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)-(88-58-4) EPA Substance Registry System 1,4-Benzenediol, 2,5-bis(1,1-dimethylethyl)- (88-58-4)   Safety Information Hazard Codes  Xi,Xn Risk Statements  36/37/38-22 Safety Statements  26-24/25 WGK Germany  3 RTECS  MX5160000 Autoignition Temperature 790 °F Hazard Note  Irritant TSCA  Yes HS Code  29072900 MSDS Information Provider Language Dibutylhydroquinone English ACROS English SigmaAldrich English ALFA English   2,5-Di-tert-butylhydroquinone Usage And Synthesis Chemical Properties cream or pale brown solid Uses 2,5-Di-tert-butylhydroquinone is the oxidation substrate used to measure the catalytic activity of the copper(II) enzyme-like catalysts. Definition ChEBI: A member of the class of hydroquinones that is benzene-1,4-diol substituted by tert-butyl groups at position 2 and 5. General Description Mobilizes Ca2+ specifically from the Ins(1,4,5)P3-sensitive Ca2+ stores by inhibiting microsomal and sarcoplasmic reticulum Ca2+-ATPase activity. Does not affect mitochondrial Ca2+ fluxes or plasma membrane Ca2+/Mg2+ ATPase activity. Useful for the study of endomembrane Ca2+ stores and plasma membrane Ca2+ permeability pathways. Biological Activity A selective inhibitor of endoplasmic reticulum Ca 2+ -ATPase. Biochem/physiol Actions 2,5-Di-tert-butylhydroquinone specifically inhibits the sarcoplasmic reticulum (SR) Ca2+ uptake in the rat ventricle. Purification Methods Crystallise the hydroquinone from *C6H6 or AcOH. [Beilstein 6 III 4741.]   2,5-Di-tert-butylhydroquinone Preparation Products And Raw materials Raw materials Hydroquinone-->ISOBUTYLENE-->1,4-Benzenediol, 2-(1,1-dimethylethyl)-5-(2-propen-1-yl)--->2,5-Di-tert-butyl-1,4-benzoquinone-->Allyltributyltin Preparation Products 6-BROMO-1H-INDOLE-2-CARBALDEHYDE-->(6-BROMO-1H-INDOL-2-YL)METHANOL-->6-Bromoindole-2-carboxylic acid-->Ethyl 6-bromoindole-2-carboxylate-->tert-Butylhydroquinone-->2,6-di-tert-butylhydroquinone-->Phenyl-t-butylether