China Largest Manufacturer factory sales Lipase CAS 9001-62-1 for 500MT/Year CAS NO.9001-62-1

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Lipase Basic information Description References Product Name: Lipase Synonyms: LIPASE AS;LIPASE AK;LIPASE AYS;LIPASE CAL-A, THERMOSTABLE;LIPASE CAL-B;LIPASE M 10;LIPASE MML;LIPASE PS CAS: 9001-62-1 MF: C11H9N3NaO2+ MW: 238.19783 EINECS: 232-619-9 Product Categories: Yellow powder;Diagnostic and Analytical EnzymesSpecialty Synthesis;Hydrolases;Specialty Enzymes;HydrolasesApplication Index;Pyrrolines ,Isoquinolines ,Heterocyclic Acids,Quinolines ,Quinaldines;Diagnostic and Analytical EnzymesApplication Index;Novozymes: Quality Environmentally-Friendly EnzymesEnzyme Class Index;Analytical Enzymes;Enzyme-Mediated Synthesis;Specialty Synthesis;HydrolasesEnzyme Class Index;Enzyme Class Index;Others;3.1.x.x Acting on esters;3.x.x.x Hydrolases;Application Index;Enzymes, Inhibitors, and Substrates;Organic Synthesis and Immobilized Enzymes;Organic SynthesisEnzyme Class Index Mol File: 9001-62-1.mol   Lipase Chemical Properties density  1.2 storage temp.  2-8°C solubility  H2O: 2 mg/mL, hazy with insoluble particles, faintly yellow form  solution color  yellow-brown Water Solubility  It is soluble in water. Merck  13,5533 Stability: Moisture sensitive. Incompatible with strong oxidizing agents. CAS DataBase Reference 9001-62-1 EPA Substance Registry System Lipase, triacylglycerol (9001-62-1)   Safety Information Hazard Codes  B,Xn Risk Statements  20/21/22 Safety Statements  22-24/25-36/37-36 WGK Germany  3 RTECS  TO9776500 F  3-10-21 TSCA  Yes HS Code  35079020 MSDS Information Provider Language Lipase English SigmaAldrich English   Lipase Usage And Synthesis Description Lipase is an enzyme and belongs to the class of hydrolase. Lipase is produced in the pancreas, mouth, and stomach.  It catalyzes the hydrolysis of triglycerides to glycerol and free fatty acids. The body uses lipase to break down fats in food so they can be absorbed in the intestines. Lipases are widely employed to catalyze hydrolysis, alcoholysis, esterification, interesterification, acidolysis and transesterification of carboxylic esters. Their unique characteristics include substrate specificity, stereospecificity, regioselectivity and ability to catalyze a heterogeneous reaction at the interface of water soluble and water insoluble systems. Lipases are used as flavor and aroma constituents in the food industry, to produce valuable oleo chemical species for diesel engines,  as additives in cosmetic formulations, to remove the pitch from pulp produced in the paper industry, for the hydrolysis of milk fat in the dairy industry, to remove non-cellulosic impurities from raw cotton before further processing into dyed and finished products, for the drug formulations in the pharmaceutical industry, and to remove subcutaneous fat in the leather industry. Lipases are also used to diagnose pancreatitis in patients. Clinically lipases help a person who has cystic fibrosis, Alzheimer's disease, atherosclerosis and act as a candidate target for cancer prevention and therapy. Lipases are also used to treat obesity in recent years. References [1] # [2] Tianwei Tan, Jike Lu, Kaili Nie, Li Deng, Fang Wang (2010) Biodiesel production with immobilized lipase: A reveiw, 28, 628-634 [3] G. D. Haki, S. K. Rakshit (2003) Developments in industrially important thermostable enzymes: a rview, 89, 17-34 [4] Jack M. Goldberg (1976) Diagnostic use of pancreatic lipase determination by radial enzyme diffusion, and design of a routine pancreatic profile, 22, 638-642 [5] H. Loli, SK. Narwal, NK. Saun, R. Gupta (2015) Lipases in medicine: an overview, 15, 1209-1216 Description Lipase is obtained from two primary sources: (1) the edible fore stomach tissue of calves, kids, or lambs and; (2 ) animal pancreatic tissue. It is produced as purified edible tissue preparations or as aqueous extracts. It is dispersible in water and insoluble in alcohol. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Description Produced by the controlled fermentation of Aspergillus niger var. as an off-white to tan amorphous powder. Soluble in water (the solution is usually light yellow), but practically insoluble in alco hol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Description Produced by the controlled fermentation of Aspergillus oryzae var. as an off-white to tan amorphous powder or a liquid. Soluble in water (the solution is usually light yellow), but practically insol uble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Description Produced by the controlled fermentation of Candida rugosa as an off-white to tan powder. Soluble in water but practically insoluble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Chemical Properties powder Uses To split fats without damaging sensitive constituents, such as vitamins or unsaturated fatty acids. In food processing for flavor improvement; in detergents for the improvement of cleaning action. For review of industrial applications of microbial lipases, see Seitz, J. Am. Oil Chem. Soc. 51, 12 (1974). Uses Trans fatty acids (TFAs) are fatty acids with at least one double bond in (E)- configuration. The consumption of TFAs increases the risk of coronary heart diseases. Thus, their concentrations in lipid-containing products should be reduced [87]. Naturally, TFAs occur in small amounts in meat and milk of ruminants, but the most significant concentrations of TFAs develop during partial hydrogenation and deodorization of fats [88]. The formation of TFAs during fat hardening can be avoided by lipase catalyzed transesterification to increase the slip melting points of fats. For enzymatic transesterification between different lipids, triacylglycerol lipases (triacylglycerol acylhydrolase, EC 3.1.1.3) acting on the SN1 and SN3 positions of the triglyceride are used. Various lipases have been applied for the production of table margarine out of fat-oil blends. Lipases of the ascomycetes Thermomyces lanuginosa and Rhizomucor miehei, as well as a lipase of the proteobacterium Pseudomonas sp., were used for transesterification of fat blends consisting of palm stearin and vegetable oil. Fully hydrogenated oils in blends with vegetable oils also have been used. In all studies, an increase of the slip melting points and the solid fat content was achieved in the fat-oil blend, thus indicating an alternative method for fat hardening via hydrogenation. Uses Lipase, is used as a catalyst in the preparation of biodiesels and in the preparation of esters of chiral epoxy alcohols. Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel. Definition lipase: An enzyme secreted by thepancreas and the glands of the smallintestine of vertebrates that catalysesthe breakdown of fats into fatty acidsand glycerol. General Description Pancrelipase (Cotazym) has agreater lipolytic action than other pancreatic enzyme preparations.Hence, it is used to help control steatorrhea and inother conditions in which pancreatic insufficiency impairsthe digestion of fats in the diet. Biochem/physiol Actions Amano lipase M is capable of catalyzing Michael addition of pyrimidine with disaccharide acrylates in organic media.   Lipase Preparation Products And Raw materials Raw materials Chloroform-->Ammonium sulfate Preparation Products Linolenic acid-->((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one-->(4S)-HYDROXY-3-METHYL-2-(2-PROPENYL)-2-CYCLOPENTENE-1-ONE-->CHILLIORANGE-->CAPSANTHIN-->Enzyme-modified milkfat-->MONASCUS RED-->(4S)-4-hydroxy-3-methyl-2-prop-2-ynyl-cyclopent-2-en-1-one-->S-α-cyano-3-phenoxy benzyl alcohol-->cellulase-->Glycerides, C10-18

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Lipase Basic information Description References Product Name: Lipase Synonyms: LIPASE AS;LIPASE AK;LIPASE AYS;LIPASE CAL-A, THERMOSTABLE;LIPASE CAL-B;LIPASE M 10;LIPASE MML;LIPASE PS CAS: 9001-62-1 MF: C11H9N3NaO2+ MW: 238.19783 EINECS: 232-619-9 Product Categories: Yellow powder;Diagnostic and Analytical EnzymesSpecialty Synthesis;Hydrolases;Specialty Enzymes;HydrolasesApplication Index;Pyrrolines ,Isoquinolines ,Heterocyclic Acids,Quinolines ,Quinaldines;Diagnostic and Analytical EnzymesApplication Index;Novozymes: Quality Environmentally-Friendly EnzymesEnzyme Class Index;Analytical Enzymes;Enzyme-Mediated Synthesis;Specialty Synthesis;HydrolasesEnzyme Class Index;Enzyme Class Index;Others;3.1.x.x Acting on esters;3.x.x.x Hydrolases;Application Index;Enzymes, Inhibitors, and Substrates;Organic Synthesis and Immobilized Enzymes;Organic SynthesisEnzyme Class Index Mol File: 9001-62-1.mol   Lipase Chemical Properties density  1.2 storage temp.  2-8°C solubility  H2O: 2 mg/mL, hazy with insoluble particles, faintly yellow form  solution color  yellow-brown Water Solubility  It is soluble in water. Merck  13,5533 Stability: Moisture sensitive. Incompatible with strong oxidizing agents. CAS DataBase Reference 9001-62-1 EPA Substance Registry System Lipase, triacylglycerol (9001-62-1)   Safety Information Hazard Codes  B,Xn Risk Statements  20/21/22 Safety Statements  22-24/25-36/37-36 WGK Germany  3 RTECS  TO9776500 F  3-10-21 TSCA  Yes HS Code  35079020 MSDS Information Provider Language Lipase English SigmaAldrich English   Lipase Usage And Synthesis Description Lipase is an enzyme and belongs to the class of hydrolase. Lipase is produced in the pancreas, mouth, and stomach.  It catalyzes the hydrolysis of triglycerides to glycerol and free fatty acids. The body uses lipase to break down fats in food so they can be absorbed in the intestines. Lipases are widely employed to catalyze hydrolysis, alcoholysis, esterification, interesterification, acidolysis and transesterification of carboxylic esters. Their unique characteristics include substrate specificity, stereospecificity, regioselectivity and ability to catalyze a heterogeneous reaction at the interface of water soluble and water insoluble systems. Lipases are used as flavor and aroma constituents in the food industry, to produce valuable oleo chemical species for diesel engines,  as additives in cosmetic formulations, to remove the pitch from pulp produced in the paper industry, for the hydrolysis of milk fat in the dairy industry, to remove non-cellulosic impurities from raw cotton before further processing into dyed and finished products, for the drug formulations in the pharmaceutical industry, and to remove subcutaneous fat in the leather industry. Lipases are also used to diagnose pancreatitis in patients. Clinically lipases help a person who has cystic fibrosis, Alzheimer's disease, atherosclerosis and act as a candidate target for cancer prevention and therapy. Lipases are also used to treat obesity in recent years. References [1] # [2] Tianwei Tan, Jike Lu, Kaili Nie, Li Deng, Fang Wang (2010) Biodiesel production with immobilized lipase: A reveiw, 28, 628-634 [3] G. D. Haki, S. K. Rakshit (2003) Developments in industrially important thermostable enzymes: a rview, 89, 17-34 [4] Jack M. Goldberg (1976) Diagnostic use of pancreatic lipase determination by radial enzyme diffusion, and design of a routine pancreatic profile, 22, 638-642 [5] H. Loli, SK. Narwal, NK. Saun, R. Gupta (2015) Lipases in medicine: an overview, 15, 1209-1216 Description Lipase is obtained from two primary sources: (1) the edible fore stomach tissue of calves, kids, or lambs and; (2 ) animal pancreatic tissue. It is produced as purified edible tissue preparations or as aqueous extracts. It is dispersible in water and insoluble in alcohol. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Description Produced by the controlled fermentation of Aspergillus niger var. as an off-white to tan amorphous powder. Soluble in water (the solution is usually light yellow), but practically insoluble in alco hol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Description Produced by the controlled fermentation of Aspergillus oryzae var. as an off-white to tan amorphous powder or a liquid. Soluble in water (the solution is usually light yellow), but practically insol uble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Description Produced by the controlled fermentation of Candida rugosa as an off-white to tan powder. Soluble in water but practically insoluble in alcohol, chloroform or ether. The major active principle is lipase, IUB No. 3.1.1.3, CAS No. 9001-62-1. Chemical Properties powder Uses To split fats without damaging sensitive constituents, such as vitamins or unsaturated fatty acids. In food processing for flavor improvement; in detergents for the improvement of cleaning action. For review of industrial applications of microbial lipases, see Seitz, J. Am. Oil Chem. Soc. 51, 12 (1974). Uses Trans fatty acids (TFAs) are fatty acids with at least one double bond in (E)- configuration. The consumption of TFAs increases the risk of coronary heart diseases. Thus, their concentrations in lipid-containing products should be reduced [87]. Naturally, TFAs occur in small amounts in meat and milk of ruminants, but the most significant concentrations of TFAs develop during partial hydrogenation and deodorization of fats [88]. The formation of TFAs during fat hardening can be avoided by lipase catalyzed transesterification to increase the slip melting points of fats. For enzymatic transesterification between different lipids, triacylglycerol lipases (triacylglycerol acylhydrolase, EC 3.1.1.3) acting on the SN1 and SN3 positions of the triglyceride are used. Various lipases have been applied for the production of table margarine out of fat-oil blends. Lipases of the ascomycetes Thermomyces lanuginosa and Rhizomucor miehei, as well as a lipase of the proteobacterium Pseudomonas sp., were used for transesterification of fat blends consisting of palm stearin and vegetable oil. Fully hydrogenated oils in blends with vegetable oils also have been used. In all studies, an increase of the slip melting points and the solid fat content was achieved in the fat-oil blend, thus indicating an alternative method for fat hardening via hydrogenation. Uses Lipase, is used as a catalyst in the preparation of biodiesels and in the preparation of esters of chiral epoxy alcohols. Lipases are used industrially for the resolution of chiral compounds and the transesterification production of biodiesel. Definition lipase: An enzyme secreted by thepancreas and the glands of the smallintestine of vertebrates that catalysesthe breakdown of fats into fatty acidsand glycerol. General Description Pancrelipase (Cotazym) has agreater lipolytic action than other pancreatic enzyme preparations.Hence, it is used to help control steatorrhea and inother conditions in which pancreatic insufficiency impairsthe digestion of fats in the diet. Biochem/physiol Actions Amano lipase M is capable of catalyzing Michael addition of pyrimidine with disaccharide acrylates in organic media.   Lipase Preparation Products And Raw materials Raw materials Chloroform-->Ammonium sulfate Preparation Products Linolenic acid-->((1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one-->(4S)-HYDROXY-3-METHYL-2-(2-PROPENYL)-2-CYCLOPENTENE-1-ONE-->CHILLIORANGE-->CAPSANTHIN-->Enzyme-modified milkfat-->MONASCUS RED-->(4S)-4-hydroxy-3-methyl-2-prop-2-ynyl-cyclopent-2-en-1-one-->S-α-cyano-3-phenoxy benzyl alcohol-->cellulase-->Glycerides, C10-18