China Biggest Manufacturer factory sales Propyleneglycol alginate(PGA) CAS 9005-37-2 CAS NO.9005-37-2

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Propyleneglycol alginate Basic information Product Name: Propyleneglycol alginate Synonyms: alginicacidpropyleneglycolester;femanumber2941;kelcoloid;kelcoloidhvf;manucolestere/rep;propylenealginate;propyleneglycolalginateester;1,2-Propanediol alginate CAS: 9005-37-2 MF: (C9H14O70n MW: 0 EINECS:   Product Categories: stabilizer Mol File: Mol File   Propyleneglycol alginate Chemical Properties Boiling point  886.32°C (rough estimate) density  1.2096 (rough estimate) FEMA  2941 | PROPYLENE GLYCOL ALGINATE refractive index  1.7040 (estimate) solubility  Soluble in dilute organic acids and water, forming stable, viscous, colloidal solutions at pH 3. Depending upon the degree of esterification, propylene glycol alginate is also soluble in aqueous ethanol/water mixtures containing up to 60% w/w of ethanol (95%). PH pH(1%, 25℃):3.5～4.5 CAS DataBase Reference 9005-37-2 EPA Substance Registry System Propylene glycol alginate (9005-37-2)   Safety Information Hazardous Substances Data 9005-37-2(Hazardous Substances Data) MSDS Information   Propyleneglycol alginate Usage And Synthesis Chemical Properties Propylene glycol alginate occurs as a white to yellowish colored, practically odorless and tasteless, fibrous or granular powder. Chemical Properties Propylene glycol alginate is practically odorless and tasteless. The propylene glycol ester of alginic acid varies in composition according to its degree of esterification and the percentages of free and neutralized carboxyl groups in the molecule. For a detailed description of this compound refer to Burdock (1997). Uses Pharmaceutic aid (suspending agent); pharmaceutic aid (viscosity-increasing agent). Uses Propylene Glycol Alginate is a gum that is the propylene glycol ester of alginic acid, which is obtained from kelp. as compared to sodium alginates, it has reduced sensitivity to acid and calcium salts. it functions in acidic systems. it functions as a thickener, stabilizer, and emulsifier in beer, salad dressings, syrups, and fruit drinks. Preparation Derived from brown algae, also from alginic acid Production Methods Alginic acid, extracted from brown seaweed, is reacted with propylene oxide to form propylene glycol alginate. Various grades may be obtained that differ in composition according to the degree of esterification and the percentage of free and neutralized carboxyl groups present in the molecule; complete esterification of alginic acid is impractical. Pharmaceutical Applications Propylene glycol alginate is used as a stabilizing, suspending, gelling, and emulsifying agent in oral and topical pharmaceutical formulations. Typically, a concentration of 0.3–5% w/v is used, although this may vary depending upon the specific application and the grade of propylene glycol alginate used. Propylene glycol alginate is also used in cosmetics and food products. Safety Profile Mddly toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes. Safety Propylene glycol alginate is used in oral and topical pharmaceutical formulations, cosmetics, and food products. It is generally regarded as a nontoxic and nonirritant material, although excessive oral consumption may be harmful. A study in five healthy male volunteers fed a daily intake of 175 mg/kg body-weight of propylene glycol alginate for 7 days, followed by a daily intake of 200 mg/kg body-weight of propylene glycol alginate for a further 16 days, showed no significant adverse effects. Inhalation of alginate dust may be irritant and has been associated with industrially related asthma in workers involved in alginate production. However, it appears that the cases of asthma were linked to exposure to seaweed dust rather than pure alginate dust. (hamster, oral): 7.0 g/kg (mouse, oral): 7.8 g/kg (rabbit, oral): 7.6 g/kg (rat, oral): 7.2 g/kg storage Propylene glycol alginate is a stable material, although it will gradually become less soluble if stored at elevated temperatures for extended periods. Propylene glycol alginate solutions are most stable at pH 3–6. In alkaline solutions, propylene glycol alginate is rapidly saponified. Alginate solutions are susceptible to microbial spoilage and should be sterilized or preserved with an antimicrobial preservative. However, sterilization processes may adversely affect the viscosity of propylene glycol alginate solutions; see Sodium Alginate. The bulk material should be stored in an airtight container in a cool, dry place. Regulatory Status GRAS listed. Accepted in Europe for use as a food additive. Included in the FDA Inactive Ingredients Database (oral preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Propyleneglycol alginate Preparation Products And Raw materials Raw materials Propylene oxide-->Propane-->Sodium alginate-->Alginic acid

                                      Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Propyleneglycol alginate Basic information Product Name: Propyleneglycol alginate Synonyms: alginicacidpropyleneglycolester;femanumber2941;kelcoloid;kelcoloidhvf;manucolestere/rep;propylenealginate;propyleneglycolalginateester;1,2-Propanediol alginate CAS: 9005-37-2 MF: (C9H14O70n MW: 0 EINECS:   Product Categories: stabilizer Mol File: Mol File   Propyleneglycol alginate Chemical Properties Boiling point  886.32°C (rough estimate) density  1.2096 (rough estimate) FEMA  2941 | PROPYLENE GLYCOL ALGINATE refractive index  1.7040 (estimate) solubility  Soluble in dilute organic acids and water, forming stable, viscous, colloidal solutions at pH 3. Depending upon the degree of esterification, propylene glycol alginate is also soluble in aqueous ethanol/water mixtures containing up to 60% w/w of ethanol (95%). PH pH(1%, 25℃):3.5～4.5 CAS DataBase Reference 9005-37-2 EPA Substance Registry System Propylene glycol alginate (9005-37-2)   Safety Information Hazardous Substances Data 9005-37-2(Hazardous Substances Data) MSDS Information   Propyleneglycol alginate Usage And Synthesis Chemical Properties Propylene glycol alginate occurs as a white to yellowish colored, practically odorless and tasteless, fibrous or granular powder. Chemical Properties Propylene glycol alginate is practically odorless and tasteless. The propylene glycol ester of alginic acid varies in composition according to its degree of esterification and the percentages of free and neutralized carboxyl groups in the molecule. For a detailed description of this compound refer to Burdock (1997). Uses Pharmaceutic aid (suspending agent); pharmaceutic aid (viscosity-increasing agent). Uses Propylene Glycol Alginate is a gum that is the propylene glycol ester of alginic acid, which is obtained from kelp. as compared to sodium alginates, it has reduced sensitivity to acid and calcium salts. it functions in acidic systems. it functions as a thickener, stabilizer, and emulsifier in beer, salad dressings, syrups, and fruit drinks. Preparation Derived from brown algae, also from alginic acid Production Methods Alginic acid, extracted from brown seaweed, is reacted with propylene oxide to form propylene glycol alginate. Various grades may be obtained that differ in composition according to the degree of esterification and the percentage of free and neutralized carboxyl groups present in the molecule; complete esterification of alginic acid is impractical. Pharmaceutical Applications Propylene glycol alginate is used as a stabilizing, suspending, gelling, and emulsifying agent in oral and topical pharmaceutical formulations. Typically, a concentration of 0.3–5% w/v is used, although this may vary depending upon the specific application and the grade of propylene glycol alginate used. Propylene glycol alginate is also used in cosmetics and food products. Safety Profile Mddly toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating fumes. Safety Propylene glycol alginate is used in oral and topical pharmaceutical formulations, cosmetics, and food products. It is generally regarded as a nontoxic and nonirritant material, although excessive oral consumption may be harmful. A study in five healthy male volunteers fed a daily intake of 175 mg/kg body-weight of propylene glycol alginate for 7 days, followed by a daily intake of 200 mg/kg body-weight of propylene glycol alginate for a further 16 days, showed no significant adverse effects. Inhalation of alginate dust may be irritant and has been associated with industrially related asthma in workers involved in alginate production. However, it appears that the cases of asthma were linked to exposure to seaweed dust rather than pure alginate dust. (hamster, oral): 7.0 g/kg (mouse, oral): 7.8 g/kg (rabbit, oral): 7.6 g/kg (rat, oral): 7.2 g/kg storage Propylene glycol alginate is a stable material, although it will gradually become less soluble if stored at elevated temperatures for extended periods. Propylene glycol alginate solutions are most stable at pH 3–6. In alkaline solutions, propylene glycol alginate is rapidly saponified. Alginate solutions are susceptible to microbial spoilage and should be sterilized or preserved with an antimicrobial preservative. However, sterilization processes may adversely affect the viscosity of propylene glycol alginate solutions; see Sodium Alginate. The bulk material should be stored in an airtight container in a cool, dry place. Regulatory Status GRAS listed. Accepted in Europe for use as a food additive. Included in the FDA Inactive Ingredients Database (oral preparations). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.   Propyleneglycol alginate Preparation Products And Raw materials Raw materials Propylene oxide-->Propane-->Sodium alginate-->Alginic acid