China Biggest Manufacturer factory sales Creatine Phosphate Sodium CAS 922-32-7 CAS NO.922-32-7

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Creatine phosphate disodium salt Basic information Description Uses Product Name: Creatine phosphate disodium salt Synonyms: Phosphocreatine Sodium Salt Creatine Phosphate Sodium Salt Sodium Phosphocreatine;SodiuM 2-(1-Methylguanidino)acetate hydrogenphosphate tetrahydrate;Glycine,N-[iMino(phosphonoaMino)Methyl]-N-Methyl-, sodiuM salt (1:2);CREATINE PHOSPHATE SODIUM FOR LNJECTION;DISODIUM [(CARBOXYMETHYL)(METHYL)AMINO](IMINO)METHYLAMIDOPHOSPHATE;Sodium Creatine Phosphate Sodium Phosphocreatine Phosphocreatine Sodium Salt;Creatine phosphate disodium salt and Intermediates;SODIUM PHOSPHOCREATINE CAS: 922-32-7 MF: C4H11N3NaO5P MW: 235.11 EINECS: 213-074-6 Product Categories: Imidazoles Mol File: 922-32-7.mol   Creatine phosphate disodium salt Chemical Properties storage temp.  Inert atmosphere,2-8°C solubility  H2O: 0.1 g/mL, clear, colorless form  Powder color  White PH pH : 8.3 (20% in water) Water Solubility  soluble InChIKey HUWYWJSJJDCZRQ-UHFFFAOYSA-L CAS DataBase Reference 922-32-7(CAS DataBase Reference)   Safety Information Hazard Codes  Xn Risk Statements  20/21/22-36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  3 F  10 HS Code  29252900 MSDS Information Provider Language Creatine phosphate disodium salt English   Creatine phosphate disodium salt Usage And Synthesis Description Creatine phosphate belongs to the human body and is the most important type of energy supplier. It can provide energy support for various tissues and organs. In human brain, kidney, cardiac muscle and skeletal muscle, 80% of the energy source is creatine phosphate. In humans, the synthesis of creatine phosphate begins in the kidney organs. A guanidinic acid is formed from arginine and glycine, and then creatine is formed through methylation in the liver. Finally, it is phosphorylated in various cellular tissues. And creatine phosphate is formed. Creatine phosphate disodium salt is a commercial creatine phosphate drug, which has become more and more widely used in acute myocardial infarction in recent years, and has achieved good results. Uses Creatine phosphate disodium salt is a white needle-like crystalline powder that is easily soluble in water. In medicine, it can protect the heart muscle by injecting creatine phosphate disodium salt, and can also be used to treat myocardial abnormalities in the ischemic state. creatine phosphate plays an important role in energy metabolism during muscle contraction[3]. The use of creatine phosphate is generally by intravenous injection. Phosphocreatine disodium salt exists as creatine phosphate after entering the body. Chemical Properties white powder Uses Creatine Phosphate Disodium Salt is an impurity of Creatine(C781483). Creatine can be used in biological study of high fat diets with different ketogenic ratios on hippocampal accumulation of creatine. Purification Methods The salt first appears as oily droplets which slowly settle and crystallise. After 12hours the supernatant is clear. Stirring and scratching the flask containing the filtrate brings out additional crystals (0.3-1g) if the salt is kept at 20o for 12hours. Filter it off at room temperature, wash with 3 x 5mL of ice-cold 90% EtOH, then 5mL of absolute EtOH and dry it in a vacuum desiccator (Drierite or CaCl2) for 16-30hours. The hexahydrate (plates) is converted to the tetrahydrate salt (needles) in a vacuum at -10o. [Ennor & Stocken Biochemical Preparations 5 9 1957, Biochem J 43 190 1958, Beilstein 4 III 1170, 4 IV 2425.]   Creatine phosphate disodium salt Preparation Products And Raw materials Raw materials Sodium hydroxide-->Hydrochloric acid-->Phosphorus oxychloride-->Sodium sulfate-->Barium chloride dihydrate-->Creatine monohydrate

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Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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Creatine phosphate disodium salt Basic information Description Uses Product Name: Creatine phosphate disodium salt Synonyms: Phosphocreatine Sodium Salt Creatine Phosphate Sodium Salt Sodium Phosphocreatine;SodiuM 2-(1-Methylguanidino)acetate hydrogenphosphate tetrahydrate;Glycine,N-[iMino(phosphonoaMino)Methyl]-N-Methyl-, sodiuM salt (1:2);CREATINE PHOSPHATE SODIUM FOR LNJECTION;DISODIUM [(CARBOXYMETHYL)(METHYL)AMINO](IMINO)METHYLAMIDOPHOSPHATE;Sodium Creatine Phosphate Sodium Phosphocreatine Phosphocreatine Sodium Salt;Creatine phosphate disodium salt and Intermediates;SODIUM PHOSPHOCREATINE CAS: 922-32-7 MF: C4H11N3NaO5P MW: 235.11 EINECS: 213-074-6 Product Categories: Imidazoles Mol File: 922-32-7.mol   Creatine phosphate disodium salt Chemical Properties storage temp.  Inert atmosphere,2-8°C solubility  H2O: 0.1 g/mL, clear, colorless form  Powder color  White PH pH : 8.3 (20% in water) Water Solubility  soluble InChIKey HUWYWJSJJDCZRQ-UHFFFAOYSA-L CAS DataBase Reference 922-32-7(CAS DataBase Reference)   Safety Information Hazard Codes  Xn Risk Statements  20/21/22-36/37/38 Safety Statements  22-24/25-36-26 WGK Germany  3 F  10 HS Code  29252900 MSDS Information Provider Language Creatine phosphate disodium salt English   Creatine phosphate disodium salt Usage And Synthesis Description Creatine phosphate belongs to the human body and is the most important type of energy supplier. It can provide energy support for various tissues and organs. In human brain, kidney, cardiac muscle and skeletal muscle, 80% of the energy source is creatine phosphate. In humans, the synthesis of creatine phosphate begins in the kidney organs. A guanidinic acid is formed from arginine and glycine, and then creatine is formed through methylation in the liver. Finally, it is phosphorylated in various cellular tissues. And creatine phosphate is formed. Creatine phosphate disodium salt is a commercial creatine phosphate drug, which has become more and more widely used in acute myocardial infarction in recent years, and has achieved good results. Uses Creatine phosphate disodium salt is a white needle-like crystalline powder that is easily soluble in water. In medicine, it can protect the heart muscle by injecting creatine phosphate disodium salt, and can also be used to treat myocardial abnormalities in the ischemic state. creatine phosphate plays an important role in energy metabolism during muscle contraction[3]. The use of creatine phosphate is generally by intravenous injection. Phosphocreatine disodium salt exists as creatine phosphate after entering the body. Chemical Properties white powder Uses Creatine Phosphate Disodium Salt is an impurity of Creatine(C781483). Creatine can be used in biological study of high fat diets with different ketogenic ratios on hippocampal accumulation of creatine. Purification Methods The salt first appears as oily droplets which slowly settle and crystallise. After 12hours the supernatant is clear. Stirring and scratching the flask containing the filtrate brings out additional crystals (0.3-1g) if the salt is kept at 20o for 12hours. Filter it off at room temperature, wash with 3 x 5mL of ice-cold 90% EtOH, then 5mL of absolute EtOH and dry it in a vacuum desiccator (Drierite or CaCl2) for 16-30hours. The hexahydrate (plates) is converted to the tetrahydrate salt (needles) in a vacuum at -10o. [Ennor & Stocken Biochemical Preparations 5 9 1957, Biochem J 43 190 1958, Beilstein 4 III 1170, 4 IV 2425.]   Creatine phosphate disodium salt Preparation Products And Raw materials Raw materials Sodium hydroxide-->Hydrochloric acid-->Phosphorus oxychloride-->Sodium sulfate-->Barium chloride dihydrate-->Creatine monohydrate