China Largest Manufacturer factory sales ITACONIC ACID CAS 97-65-4 CAS NO.97-65-4

                                PRODUCT DETAILS                           

Itaconic acid Basic information Product Name: Itaconic acid Synonyms: methylene-butanedioicaci;methylene-succinicaci;Succinic acid, methylene-;3-CARBOXY-3-BUTENOIC ACID;METHYLENESUCCINIC ACID;ITACONIC ACID;2-PROPENE-1,2-DICARBOXYLIC ACID;PROPYLENEDICARBOXYLIC ACID CAS: 97-65-4 MF: C5H6O4 MW: 130.1 EINECS: 202-599-6 Product Categories: Building Blocks;C1 to C5;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks;Organic Chemicals;Pyridines Mol File: 97-65-4.mol   Itaconic acid Chemical Properties Melting point  165-168 °C (lit.) Boiling point  268°C density  1.573 g/mL at 25 °C (lit.) vapor pressure  0.0000115 Pa (20 °C) refractive index  1.4980 (estimate) Fp  268°C storage temp.  Store below +30°C. solubility  77.49g/l pka 3.85(at 25℃) form  Crystalline Powder or Crystals color  White to light beige Specific Gravity 1.573 PH 3.5(1 mM solution);2.95(10 mM solution);2.43(100 mM solution); Water Solubility  Soluble in water, acetone, methanol, hexane and ethanol. Slightly soluble in benzene, chloroform, carbon disulfide and petroleum ether. Sensitive  Hygroscopic Merck  14,5242 BRN  1759501 Stability: Light Sensitive InChIKey LVHBHZANLOWSRM-UHFFFAOYSA-N CAS DataBase Reference 97-65-4(CAS DataBase Reference) NIST Chemistry Reference Butanedioic acid, methylene-(97-65-4) EPA Substance Registry System Itaconic acid (97-65-4)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36 WGK Germany  1 Autoignition Temperature 430 °C TSCA  Yes HS Code  29171990 Hazardous Substances Data 97-65-4(Hazardous Substances Data) Toxicity LD50 orally in Rabbit: > 2000 mg/kg MSDS Information Provider Language Methylenebutanedioic acid English SigmaAldrich English ACROS English ALFA English   Itaconic acid Usage And Synthesis Chemical Properties white to light beige crystalline powder Uses Copolymerizations, resins, plasticizers, lube-oil additive, intermediate. Uses The major uses for itaconic acid are in copolymerizations, resins, plasticizers, and as lube oil additives. Uses Itaconic acid is used in the preparation of acrylonitrile-butadiene-styrene and acrylate latexes. It is also used to prepare poly-itaconic acid, resins biofuel components and ionomer cements. It finds application in the textile, chemical and pharmaceutical industries. It is also used as an additive in fibers and ion exchange resins to increase abrasion, waterproofing, physical resistance, dying affinity and better duration. Further, it acts as a co-monomer used in the preparation of acrylic fibers and rubbers, reinforced glass fiber, artificial diamonds and lens. In addition to this, it acts as a binder and sizing agent in non-weaving fibers. Definition itaconic acid: A product of the fermentationof the flamentous fungusAspergillus niger. Itaconic acid is usedcommercially in the production ofadhesives and paints. Definition ChEBI: A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group. General Description Itaconic acid, an unsaturated dicarbonic organic acid, is a metabolic product of Aspergillus itaconicus. Purification Methods Crystallise itaconic acid from EtOH, EtOH/water or EtOH/*benzene. [Beilstein 2 IV 2228.]   Itaconic acid Preparation Products And Raw materials Raw materials Maleic anhydride-->Starch-->Succinic anhydride-->THORIUM-->Citraconic acid-->ACONITIC ACID, trans-(RG)-->ANTIOXIDANT 765 Preparation Products 1-(2-AMINOETHYL)-4-BENZYLPIPERAZINE-->Dimethyl itaconate-->Itaconic anhydride-->3-Hydroxyglutaric Acid-->propene-->Methacrylic acid-->Dimethyl (R)-(+)-methylsuccinate-->ITACONIC ACID MONO-N-BUTYL ESTER-->(R)-(+)-Methylsuccinic acid-->3-METHYLTETRAHYDROFURAN-->Itaconic acid monomethyl ester

                                                                       Group profiles

Leader Biochemical Group is a large leader incorporated industry manufacturers and suppliers of advanced refined raw materials From the year of 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & chemicals, functional active ingredients, nutritional Ingredients, health care products, cosmetics, pharmaceutical and refined feed, oil, natural plant ingredients industries to provide top quality of GMP standards products.All the invested factories' product lines cover API and intermediates, vitamins, amino acids, plant extracts, daily chemical products, cosmetics raw materials, nutrition and health care products, food additives, feed additives, essential oil products, fine chemical products and agricultural chemical raw materials And flavors and fragrances. Especially in the field of vitamins, amino acids, pharmaceutical raw materials and cosmetic raw materials, we have more than 20 years of production and sales experience. All products meet the requirements of high international export standards and have been recognized by customers all over the world. Our manufacture basement & R&D center located in National Aerospace Economic & Technical Development Zone Xi`an Shaanxi China. Now not only relying on self-cultivation and development as well as maintains good cooperative relations with many famous research institutes and universities in China. Now, we have closely cooperation with Shanghai Institute of Organic Chemistry of Chinese Academy of Science, Beijing Institute of Material Medical of Chinese Academy of Medical Science, China Pharmaceutical University, Zhejiang University. Closely cooperation with them not only integrating Science and technology resources, but also increasing the R&D speed and improving our R&D power. Offering Powerful Tech supporting Platform for group development. Keep serve the manufacture and the market as the R&D central task, focus on the technical research.  Now there are 3 technology R & D platforms including biological extract, microorganism fermentation and chemical synthesis, and can independently research and develop kinds of difficult APIs and pharmaceutical intermediates. With the strong support of China State Institute of Pharmaceutical Industry (hereinafter short for CSIPI), earlier known as Shanghai Institute of Pharmaceutical Industry (SIPI), we have unique advantages in the R & D and industrialization of high-grade, precision and advanced products.  Now our Group technical force is abundant, existing staff more that 1000 people, senior professional and technical staff accounted for more than 50% of the total number of employees, including 15 PhD research and development personnel, 5 master′ S degree in technical and management personnel 9 people. We have advanced equipment like fermentation equipment and technology also extraction, isolation, purification, synthesis with rich production experience and strict quality control system, According to the GMP required, quickly transforming the R&D results to industrial production in time, it is our advantages and our products are exported to North and South America, Europe, Middle East, Africa, and other five continents and scale the forefront in the nation, won good international reputation.  We believe only good quality can bring good cooperation, quality is our key spirit during our production, we are warmly welcome clients and partner from all over the world contact us for everlasting cooperation, Leader will be your strong, sincere and reliable partner in China.

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                                                       Product information

Itaconic acid Basic information Product Name: Itaconic acid Synonyms: methylene-butanedioicaci;methylene-succinicaci;Succinic acid, methylene-;3-CARBOXY-3-BUTENOIC ACID;METHYLENESUCCINIC ACID;ITACONIC ACID;2-PROPENE-1,2-DICARBOXYLIC ACID;PROPYLENEDICARBOXYLIC ACID CAS: 97-65-4 MF: C5H6O4 MW: 130.1 EINECS: 202-599-6 Product Categories: Building Blocks;C1 to C5;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Organic Building Blocks;Organic Chemicals;Pyridines Mol File: 97-65-4.mol   Itaconic acid Chemical Properties Melting point  165-168 °C (lit.) Boiling point  268°C density  1.573 g/mL at 25 °C (lit.) vapor pressure  0.0000115 Pa (20 °C) refractive index  1.4980 (estimate) Fp  268°C storage temp.  Store below +30°C. solubility  77.49g/l pka 3.85(at 25℃) form  Crystalline Powder or Crystals color  White to light beige Specific Gravity 1.573 PH 3.5(1 mM solution);2.95(10 mM solution);2.43(100 mM solution); Water Solubility  Soluble in water, acetone, methanol, hexane and ethanol. Slightly soluble in benzene, chloroform, carbon disulfide and petroleum ether. Sensitive  Hygroscopic Merck  14,5242 BRN  1759501 Stability: Light Sensitive InChIKey LVHBHZANLOWSRM-UHFFFAOYSA-N CAS DataBase Reference 97-65-4(CAS DataBase Reference) NIST Chemistry Reference Butanedioic acid, methylene-(97-65-4) EPA Substance Registry System Itaconic acid (97-65-4)   Safety Information Hazard Codes  Xi Risk Statements  36/37/38 Safety Statements  26-36 WGK Germany  1 Autoignition Temperature 430 °C TSCA  Yes HS Code  29171990 Hazardous Substances Data 97-65-4(Hazardous Substances Data) Toxicity LD50 orally in Rabbit: > 2000 mg/kg MSDS Information Provider Language Methylenebutanedioic acid English SigmaAldrich English ACROS English ALFA English   Itaconic acid Usage And Synthesis Chemical Properties white to light beige crystalline powder Uses Copolymerizations, resins, plasticizers, lube-oil additive, intermediate. Uses The major uses for itaconic acid are in copolymerizations, resins, plasticizers, and as lube oil additives. Uses Itaconic acid is used in the preparation of acrylonitrile-butadiene-styrene and acrylate latexes. It is also used to prepare poly-itaconic acid, resins biofuel components and ionomer cements. It finds application in the textile, chemical and pharmaceutical industries. It is also used as an additive in fibers and ion exchange resins to increase abrasion, waterproofing, physical resistance, dying affinity and better duration. Further, it acts as a co-monomer used in the preparation of acrylic fibers and rubbers, reinforced glass fiber, artificial diamonds and lens. In addition to this, it acts as a binder and sizing agent in non-weaving fibers. Definition itaconic acid: A product of the fermentationof the flamentous fungusAspergillus niger. Itaconic acid is usedcommercially in the production ofadhesives and paints. Definition ChEBI: A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group. General Description Itaconic acid, an unsaturated dicarbonic organic acid, is a metabolic product of Aspergillus itaconicus. Purification Methods Crystallise itaconic acid from EtOH, EtOH/water or EtOH/*benzene. [Beilstein 2 IV 2228.]   Itaconic acid Preparation Products And Raw materials Raw materials Maleic anhydride-->Starch-->Succinic anhydride-->THORIUM-->Citraconic acid-->ACONITIC ACID, trans-(RG)-->ANTIOXIDANT 765 Preparation Products 1-(2-AMINOETHYL)-4-BENZYLPIPERAZINE-->Dimethyl itaconate-->Itaconic anhydride-->3-Hydroxyglutaric Acid-->propene-->Methacrylic acid-->Dimethyl (R)-(+)-methylsuccinate-->ITACONIC ACID MONO-N-BUTYL ESTER-->(R)-(+)-Methylsuccinic acid-->3-METHYLTETRAHYDROFURAN-->Itaconic acid monomethyl ester